Fig. 1. Time–kill curves of imipenem and meropenem against P. aeruginosa (A) A1701DS, (B) B1707∆oprD, (C) F1709pump↑, (D) B1605∆oprD/pump↑/IMPstrains. Number of bacterial colony forming units are presented to the detection limit (102 CFU/mL). Black circle and black solid line, no antibiotics treated; gray circle and gray solid line, 1×MIC; and open circle and black broken line, 4×MIC.

Ann Clin Microbiol 2020;23:73-80. Killing Dynamics of Carbapenems against Pseudomonas aeruginosa Harboring Varied Determinants of Carbapenem Resistance

Fig. 1. Time–kill curves of imipenem and meropenem against P. aeruginosa (A) A1701_DS, (B) B1707_∆oprD, (C) F1709_pump↑, (D) B1605_{∆oprD/pump↑/IMP}strains. Number of bacterial colony forming units are presented to the detection limit (10² CFU/mL). Black circle and black solid line, no antibiotics treated; gray circle and gray solid line, 1×MIC; and open circle and black broken line, 4×MIC.