Ann Clin Microbiol 2020;23:181-189. The Trend of Clostridioides difficile Infection in Korean Hospitals with the Analysis of Nationwide Sample Cohort
| Characteristic | Cases No. (Infection rate, %) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Year | 2006 | 2007 | 2008 | 2009 | 2010 | 2011 | 2012 | 2013 | 2014 | 2015 | Total | P-value* |
| Sex | ||||||||||||
| Male | 9 (0.034) | 22 (0.070) | 27 (0.080) | 42 (0.116) | 55 (0.140) | 63 (0.150) | 118 (0.267) | 100 (0.226) | 117 (0.255) | 143 (0.301) | 696 (0.178) | <.0001 |
| Female | 8 (0.027) | 18 (0.052) | 30 (0.080) | 53 (0.133) | 82 (0.186) | 83 (0.179) | 92 (0.186) | 132 (0.267) | 119 (0.236) | 172 (0.331) | 789 (0.182) | <.0001 |
| Age (yr) | ||||||||||||
| 0-49 | 1 (0.003) | 4 (0.012) | 7 (0.020) | 11 (0.030) | 13 (0.032) | 16 (0.039) | 21 (0.050) | 14 (0.034) | 13 (0.031) | 25 (0.059) | 125 (0.033) | 0.0015 |
| 50-59 | 2 (0.025) | 4 (0.043) | 10 (0.093) | 9 (0.075) | 11 (0.079) | 10 (0.063) | 35 (0.204) | 20 (0.114) | 28 (0.156) | 30 (0.165) | 159 (0.113) | 0.0049 |
| 60-69 | 4 (0.049) | 10 (0.099) | 14 (0.131) | 12 (0.106) | 35 (0.287) | 36 (0.283) | 35 (0.252) | 36 (0.257) | 42 (0.287) | 46 (0.296) | 270 (0.219) | 0.0009 |
| 70-79 | 7 (0.102) | 9 (0.097) | 19 (0.191) | 32 (0.299) | 40 (0.345) | 44 (0.352) | 76 (0.550) | 77 (0.552) | 76 (0.533) | 104 (0.708) | 484 (0.412) | <.0001 |
| > 80 | 3 (0.113) | 13 (0.300) | 7 (0.149) | 31 (0.615) | 38 (0.673) | 40 (0.663) | 43 (0.612) | 85 (1.185) | 77 (0.993) | 110 (1.272) | 447 (0.758) | <.0001 |
| Insurance ranking | ||||||||||||
| Medical benefits | 3 (0.045) | 6 (0.075) | 10 (0.124) | 20 (0.236) | 20 (0.242) | 20 (0.241) | 36 (0.425) | 38 (0.477) | 28 (0.340) | 52 (0.647) | 233 (0.289) | 0.0001 |
| 1, 2 | 1 (0.014) | 4 (0.050) | 7 (0.085) | 12 (0.13) | 17 (0.167) | 18 (0.160) | 26 (0.215) | 29 (0.225) | 30 (0.228) | 28 (0.195) | 172 (0.162) | 0.0001 |
| 3, 4 | 3 (0.038) | 1 (0.013) | 7 (0.076) | 7 (0.070) | 23 (0.204) | 12 (0.103) | 23 (0.179) | 27 (0.221) | 24 (0.193) | 32 (0.262) | 159 (0.148) | 0.0004 |
| 5, 6 | 2 (0.022) | 11 (0.095) | 5 (0.041) | 13 (0.100) | 19 (0.133) | 18 (0.119) | 27 (0.169) | 18 (0.112) | 31 (0.186) | 45 (0.264) | 189 (0.134) | 0.0008 |
| 7, 8 | 4 (0.033) | 8 (0.056) | 10 (0.065) | 17 (0.103) | 20 (0.108) | 31 (0.161) | 44 (0.216) | 60 (0.291) | 53 (0.247) | 49 (0.222) | 296 (0.164) | <.0001 |
| 9, 10 | 4 (0.030) | 10 (0.061) | 18 (0.101) | 26 (0.137) | 38 (0.182) | 47 (0.208) | 54 (0.225) | 60 (0.251) | 70 (0.288) | 109 (0.423) | 436 (0.210) | <.0001 |
*P-value: the difference over 10 years (2006-2015).