Ann Clin Microbiol 2021;24:1-9. Educational Intervention to Improve Blood Culture Indicators in a Secondary-Care Hospital

Table 1. Comparison of indicators of blood cultures between pre- and post- educational intervention period
Variable Pre-intervention (n=9,064 bottles) Post-intervention (n=9,154 bottles) P-value
Blood volume per bottle, mL (IQR) 5.4 (4.1 – 6.5) 7.1 (5.0 – 10.1) <0.0001
Blood volume per aerobic bottle, mL (IQR) 5.3 (4.1 – 6.4) 7.7 (5.4 – 10.2) <0.0001
Blood volume per anaerobic bottle, mL (IQR) 5.5 (4.1 – 6.7) 6.4 (4.7 – 9.9) <0.0001
Blood volume per bottle by laboratory technicians, mL (IQR) 6.0 (4.5 – 7.7) 8.6 (5.4 – 10.5) <0.0001
Blood volume per bottle by emergency medical technicians, mL (IQR) 5.1 (4.0 – 6.0) 6.3 (4.9 – 9.8) <0.0001
Rate of optimal blood volume* 9.1% (157/1,725) 37.8% (3,212/8,492) <0.0001
Positive rate 9.6% (433/4,532) 9.1% (415/4,577) 0.4237
Contamination rate 0.5% (24/4,532) 1.1% (50/4,577) 0.0028
Time to detection, hr (IQR) 14.7 (11.1 – 22.6) 13.2 (10.4 – 22.1) 0.0420
Time to identification, hr (IQR) 81.6 (63.0 – 110.9) 72.2 (63.2 – 102.9) 0.0183

Number of bottles weighted by a scale was 1,725 during pre-intervention and 8,492 during post-intervention.
*Optimal blood volume is defined as 8 – 12 mL per bottle. Abbreviation: IQR, interquartile range.