Ann Clin Microbiol 2021;24:97-104. Fecal Microbiota Transplantation against Gut Colonization Using a Multidrug-Resistant Organism

Table 2. SIGN criteria for assignment of levels of grades of recommendation
Level Description
A At least one meta-analysis, systematic review, or RCT rated as 1++, and directly applicable to the target population; or a body of evidence consisting principally of studies rated as 1+, directly applicable to the target population, and demonstrating overall consistency of results
B A body of evidence including studies rated as 2++, directly applicable to the target population, and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 1++ or 1+
C A body of evidence including studies rated as 2+, directly applicable to the target population and demonstrating overall consistency of results; or extrapolated evidence from studies rated as 2++
D Evidence level 3 or 4; or extrapolated evidence from studies rated as 2+

Abbreviatons: SIGN, Scottish intercollegiate guideline network; RCT, randomized controlled trial.