Ann Clin Microbiol 2022;25:11-16. Genetic polymorphisms in the pvdhfr, pvmdr1, and pvdhps genes of Plasmodium vivax in patients at a secondary hospital in South Korea

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Table 3. Clinical course of patients with confirmed Plasmodium vivax infections
Patient No. Medication Parasite count (/μL) [FU day*]
Initial 1st FU 2nd FU 3rd FU 4th FU 5th FU
1 3 days of HCQ followed by 2 weeks of PQ 1,704 305 [2] 298 [3] negative [8]
2 3 days of HCQ followed by 2 weeks of PQ 10,903 negative [4]
3 3 days of HCQ followed by 2 weeks of PQ 6,104 518 [2] 110 [3] 26 [4] negative [5]
4 3 days of HCQ followed by 2 weeks of PQ 1,344 60 [2] 30 [3] 29 [4] 32 [5] negative [9]
5 FU loss after 3 days of AQ 63,117 FU loss
6 3 days of HCQ followed by 2 weeks of PQ 6,809 271 [4] negative [11]
7 3 days of HCQ followed by 2 weeks of PQ 8,400 426 [3] negative [14]
8 3 days of AQ followed by 2 weeks of PQ 12,247 negative [5]
9 3 days of HCQ followed by 2 weeks of PQ 9,313 3,432 [2] 195 [3] 77 [4] negative [5]
10 Transferred out after 3 days of HCQ 428 transferred
11 3 days of HCQ followed by 2 weeks of PQ 36,632 1,432 [2] 164 [3] 152 [4] negative [6]
12 3 days of HCQ followed by 2 weeks of PQ 17,889 11,289 [2] 1,234 [3] 326 [4] 197 [5] negative [6]

*Days from initial medication. Abbreviations: FU, follow-up; HCQ, hydroxycholoroquine; PQ, primaquine; AQ, atovaquone.