Characteristic | Neutralizing antibody | P-value | ||
---|---|---|---|---|
Positive (n = 9) No. (%) | Negative (n = 21) No. (%) | Total (n = 30) No. (%) | ||
Sex, male | 5 (55.6) | 8 (38.1) | 13 (43.3) | 0.630 |
Age (yr)* | 53.4 ± 9.9 | 40.8 ± 14.4 | 44.6 ± 14.3 | 0.033 |
Presentation of COVID-19 | ||||
NEWS score at admission† | 1 [0–1.5] | 0 [0–1.5] | 1 [0–1.25] | 0.504 |
Pneumonia | 8 (88.9) | 8 (38.1) | 16 (53.3) | 0.017 |
Oxygen support via nasal prong | 1 (11.1) | 0 | 1 (3.3) | 0.300 |
Asymptomatic patients | 0 | 3 (14.3) | 3 (10.0) | 0.530 |
Interval of diagnosis and sample collection(days)* | 112.7 ± 15.9 | 116.4 ± 14.5 | 115.3 ± 14.8 | 0.525 |
Ct value† | ||||
E | 19.3 [18.8–19.6] | 27.4 [22.4–30.1] | 23.2 [19.3–28.6] | 0.005 |
RdRp | 17.9 [16.9–20.0] | 27.9 [23.5–32.0] | 24.6 [17.9–29.8] | 0.003 |
N | 20.7 [19.4–22.2] | 24.0 [19.6–30.5] | 21.8 [19.6–24.0] | 0.236 |
Neutralizing antibody reciprocal titer† | 80 [80–160] | 20 [10–40] | 40 [20–80] | |
ELISA OD† | 0.89 [0.63–0.92] | 0.35 [0.26–0.45] | 0.44 [0.28–0.67] | 0.002 |