Ann Clin Microbiol 2022;25:67-72. EUCAST v.12.0 review focused on changes
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Table 2. New EUCAST v.12.0 clinical breakpoint organism-antimicrobial agent for anaerobic bacteria
OrganismAntimicrobial agent
Bacteroides spp.Piperacillin-tazobactam, Meropenem, Clindamycin, Metronidazole
Prevotella spp.Benzylpenicillin, Piperacillin-tazobactam, Meropenem, Clindamycin, Metronidazole
F. necrophorumBenzylpenicillin, Piperacillin-tazobactam, Meropenem, Clindamycin, Metronidazole
C. perfringensBenzylpenicillin, Piperacillin-tazobactam, Meropenem, Vancomycin, Clindamycin, Metronidazole
C. acnesBenzylpenicillin, Piperacillin-tazobactam, Meropenem, Vancomycin, Clindamycin
C. difficileVancomycin, Metronidazole, Fidaxomicin

Abbreviation: EUCAST, European Committee on Antimicrobial Susceptibility Testing.