Table 2. Conventional DST results and rpoB gene sequencing data of three rifampin resistant isolates with new critical concentration

Ann Clin Microbiol 2023;26:139-145. Comparative evaluation of critical concentrations for detecting borderline rifampin resistance in Mycobacterium tuberculosis

Table 2. Conventional DST results and rpoB gene sequencing data of three rifampin resistant isolates with new critical concentration

Patient No.	Date	rpoB gene Sequencing (E. coli numbering)	Conventional DST results of anti-TB drugs (CC [μg/mL])
Patient No.	Date	rpoB gene Sequencing (E. coli numbering)	INH (0.2)	INH (1.0)	SM (2.0)	EMB (5.0)	ETH (5.0)	CAP (10.0)	KM (5.0)	AMK (4.0)	OFL (2.0)	LEV (1.0)	MOX (0.5)	PAS (2.0)	RBT (0.5)	LIN (1.0)	PZA
1	2021-06-02	H445L (H526L)	S	S	S	S	S	S	S	S	R	R	R	S	S	S	S
2	2021-11-09	L452P (L533P)	R	R	S	S	S	S	S	S	S	S	S	S	R	S	S
3	2021-12-16	L452P (L533P)	R	R	S	S	S	S	S	S	S	S	S	S	R	S	S

Abbreviations: DST, drug susceptibility testing; TB, tuberculosis; CC, critical concentration; INH, isoniazid; SM, streptomycin; EMB, ethambutol; ETH, ethionamide; CAP, capreomycin; KM, kanamycin; AMK, amikacin; OFL, ofloxacin; LEV, levofloxacin; MOX, moxifloxacin; PAS, para-aminosalicylic acid; RBT, rifabutin; LIN, linezolid; PZA, pyrazinamide; S, susceptible; R, resistant.