Ann Clin Microbiol 2024;27:31-37. Emergence of Vanrija humicola as a pathogen of urinary tract infections in Korea
| Microbiological characteristics | Isolate from patient 1 | Isolate from patient 2 |
|---|---|---|
| Species Identification | ||
| MALDI Biotyper (score) | ||
| Colonies on blood agar plate | Vanrija humicola (1.37) | Vanrija humicola (1.41) |
| Colonies on Sabouraud dextrose agar | Vanrija humicola (2.04) | Vanrija humicola (1.94) |
| VITEK YST | Unidentified due to growth failure | Unidentified due to growth failure |
| API 20C AUX kit (% identification) | Cryptococcus humicola (50.5)/ Trichosporon mucoides (47.2) | Cryptococcus humicola (51.4)/ Trichosporon mucoides (48.1) |
| Sequence analysis | ||
| ITS region, Accession number* | PP178147.1 | PP188532.1 |
| First match (%identity) | Vanrija humicola FJ515176 (100) | Vanrija humicola FJ515176 (100) |
| D1/D2 region, Accession number* | PP218158.1 | PP218156.1 |
| First match (%identity) | Vanrija humicola KY110010 (99.5) | Vanrija humicola KY110010 (99.5) |
| Antifungal susceptibility, minimum inhibitory concentrations (μg/mL) | ||
| Fluconazole | 128 | 64 |
| Itraconazole | 0.5 | 0.25 |
| Voriconazole | 2 | 2 |
| Posaconazole | 1 | 0.5 |
| Caspofungin | 8 | 8 |
| Anidulafungin | 8 | 8 |
| Micafungin | 8 | 8 |
| Amphotericin B | 0.25 | 0.25 |
| 5-flucytosine | 64 | 16 |