Ann Clin Microbiol 2024;27:31-37. Emergence of Vanrija humicola as a pathogen of urinary tract infections in Korea

Table 2. Microbiological characteristics of two recent isolates of Vanrija humicola
Microbiological characteristics Isolate from patient 1 Isolate from patient 2
Species Identification
  MALDI Biotyper (score)
    Colonies on blood agar plate Vanrija humicola (1.37) Vanrija humicola (1.41)
    Colonies on Sabouraud dextrose agar Vanrija humicola (2.04) Vanrija humicola (1.94)
  VITEK YST Unidentified due to growth failure Unidentified due to growth failure
  API 20C AUX kit (% identification) Cryptococcus humicola (50.5)/ Trichosporon mucoides (47.2) Cryptococcus humicola (51.4)/ Trichosporon mucoides (48.1)
Sequence analysis
ITS region, Accession number* PP178147.1 PP188532.1
  First match (%identity) Vanrija humicola FJ515176 (100) Vanrija humicola FJ515176 (100)
D1/D2 region, Accession number* PP218158.1 PP218156.1
  First match (%identity) Vanrija humicola KY110010 (99.5) Vanrija humicola KY110010 (99.5)
Antifungal susceptibility, minimum inhibitory concentrations (μg/mL)
  Fluconazole 128 64
  Itraconazole 0.5 0.25
  Voriconazole 2 2
  Posaconazole 1 0.5
  Caspofungin 8 8
  Anidulafungin 8 8
  Micafungin 8 8
  Amphotericin B 0.25 0.25
  5-flucytosine 64 16