Ann Clin Microbiol 2026;29(3):14. Molecular epidemiological characteristics of monophasic Salmonella enterica serovar Typhimurium variants in Korea
| Antimicrobial agent | I 4,[5],12:i:1,2 (Typhimurium) | I 4,[5],12:-:- | I 4,[5],12:i:- | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| P1 (n = 32) | P2 (n = 6) | Total (n = 38) | P1 (n = 4) | P1 (n = 2) | P5 (n = 72) | P8 (n = 29) | P9 (n = 28) | Total (n = 131) | P-value (P5 vs. P8) | |||
| Amikacina) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | − | ||
| Ampicillin | 46.9 | 50.0 | 47.4 | 25.0 | 0 | 91.7 | 79.3 | 3.6 | 68.7 | 0.098 | ||
| Azithromycin | 0 | 0 | 0 | 0 | 0 | 2.8 | 0 | 0 | 1.5 | 1.000 | ||
| Cefotaxime | 3.1 | 0 | 2.6 | 0 | 0 | 13.9 | 41.4 | 3.6 | 17.6 | 0.006 | ||
| Cefoxitina) | 3.1 | 0 | 2.6 | 0 | 0 | 4.2 | 0 | 0 | 2.3 | 0.555 | ||
| Ceftazidimea) | 0 | 0 | 0 | 0 | 0 | 4.2 | 37.9 | 0 | 10.7 | < 0.001 | ||
| Ceftriaxone | 3.1 | 0 | 2.6 | 0 | 0 | 11.1 | 41.4 | 3.6 | 16.0 | 0.002 | ||
| Chloramphenicol | 25.0 | 50.0 | 28.9 | 25.0 | 0 | 31.9 | 41.4 | 0 | 26.7 | 0.489 | ||
| Ciprofloxacin (Intermediate rates, %) | 6.3 (40.6) | 16.7 (50.0) | 7.9 (42.1) | 0 (100) | 0 (0) | 0 (27.8) | 6.9 (31.0) | 0 (0) | 1.5 (22.1) | 0.080 | ||
| Colistinb) | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.1 | 1.5 | − | ||
| Gentamicina) | 28.1 | 0 | 23.7 | 25.0 | 0 | 8.3 | 0 | 0 | 4.6 | 0.178 | ||
| Imipenem | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | − | ||
| Nalidixic acida) | 43.8 | 0 | 36.8 | 100 | 0 | 0 | 3.4 | 0 | 0.8 | 0.287 | ||
| Streptomycina) | 21.9 | 33.3 | 23.7 | 25.0 | 0 | 86.1 | 79.3 | 3.6 | 65.6 | 0.385 | ||
| Tetracycline | 34.4 | 33.3 | 34.2 | 0 | 0 | 84.7 | 75.9 | 0 | 63.4 | 0.389 | ||
| Trimethoprim–sulfamethoxazole | 12.5 | 50.0 | 18.4 | 0 | 0 | 27.8 | 0 | 0 | 15.3 | < 0.001 | ||
Values are presented as percentages of resistant isolates unless otherwise indicated.
a)Clinical and Laboratory Standards Institute (CLSI) breakpoints have not been established for these antimicrobial agents; the interpretive standards used are the National Antimicrobial Resistance Monitoring System (NARMS)-established breakpoints for resistance monitoring, which should not be used to predict clinical efficacy.
b)European Committee on Antimicrobial Susceptibility Testing, 2026.