Ann Clin Microbiol 2022;25:17-23. Clinical and microbiological risk factors for severe Clostridioides difficile infections
Table 2. Risk factors for severe or severe complicated CDI over non-severe CDI: a multivariate analysis
Risk factor OR (95% CI) P-value*
Advanced age 1.017 (1.001-1.034) 0.0358
History of chemotherapy 2.695 (1.016-7.146) 0.0464
Ribotype 002 3.406 (1.183-9.803) 0.0231

*Statistical significances were maintained after the adjustment for age, associated disease (cancer, pneumonia, heart failure, nutrition deficiency), previous use of antimicrobials (penicillin, narrow-spectrum cephalosporin, carbapenem, teicoplanin), recovery, ribotype 001, ribotype 002, and ribotype 018. Abbreviations: CDI, C. difficile infection; OR, odds ratio; CI, confidence interval.