Table 5. Comparison of C. difficile growth in cultured isolates and toxin production status with GDH positivity rate

Ann Clin Microbiol 2025;28(3):14. Application of diagnostic algorithms for Clostridioides difficile infection using a GDH/ toxin test for five years from a single center in Korea: a diagnostic accuracy study

Table 5. Comparison of C. difficile growth in cultured isolates and toxin production status with GDH positivity rate

Bacterial growth	Toxin status	GDH		GDH positivity rate (%)
Bacterial growth	Toxin status	+	−	GDH positivity rate (%)
1 CFU	Toxin+	18	24	42.9
	Toxin−	12	26	28.9
2 CFU ~ few	Toxin+	161	105	60.5
	Toxin−	86	79	52.1
Some, many	Toxin+	566	38	93.7
	Toxin−	76	6	92.7

Toxin +: Toxin B PCR positive or toxigenic C. difficile isolate; Toxin −: Toxin B PCR negative or non-toxigenic isolate.
Abbreviation: GDH, glutamate dehydrogenase; CFU, colony forming unit; PCR, polymerase chain reaction.