Fig. 3. Minimal spanning tree (MSTreeV2) based on cgMLST (left) and wgMLST (right) allelic profiles of the representative S. aureus strains, illustrating relationships between major clones. The Korean clinical MRSA strains are indicated by bolded rectangles. SCCmec II strains from Korea clustered closely with other representative SCCmec II strains. In contrast, SCCmec IVA strains of CC8 (HL16278 and HL18840) formed a distinct clade, separate from other SCCmec IV reference strains of CC8 in both allelic analysis of cgMLST and wgMLST, which is consistent with the findings of SNP-based phylogenetic tree analysis. A total of 2,009 cgMLST loci and 3,567 wgMLST loci were included in this analysis. MLST: multilocus sequence typing; SCCmec: staphylococcal cassette chromosome mec; SNP: single-nucleotide polymorphism

Ann Clin Microbiol 2025;28(3):15. Complete genome analysis of representative methicillin-resistant Staphylococcus aureus clinical strains prevalent in Korea during 2014-2017

Fig. 3. Minimal spanning tree (MSTreeV2) based on cgMLST (left) and wgMLST (right) allelic profiles of the representative S. aureus strains, illustrating relationships between major clones. The Korean clinical MRSA strains are indicated by bolded rectangles. SCCmec II strains from Korea clustered closely with other representative SCCmec II strains. In contrast, SCCmec IVA strains of CC8 (HL16278 and HL18840) formed a distinct clade, separate from other SCCmec IV reference strains of CC8 in both allelic analysis of cgMLST and wgMLST, which is consistent with the findings of SNP-based phylogenetic tree analysis. A total of 2,009 cgMLST loci and 3,567 wgMLST loci were included in this analysis. MLST: multilocus sequence typing; SCCmec: staphylococcal cassette chromosome mec; SNP: single-nucleotide polymorphism