Table 1. Comparison of MICs and EA between the reference broth microdilution and Sensititre SLOMYCO panel for mycobacterial isolates

Ann Clin Microbiol 2025;28(4):24. Drug susceptibility testing of Mycobacterium avium complex using the SLOMYCO test-system: a diagnostic accuracy study

Table 1. Comparison of MICs and EA between the reference broth microdilution and Sensititre SLOMYCO panel for mycobacterial isolates

Antimicrobials	Method	No. of isolates with each MIC (µg/mL)												No. of isolates included for the EA calculation	EA (%)	95% CI of EA
Amikacin	MIC	≤1	1	2	4	8	16	32	64	>64				86	90	81.9-94.7
	Reference				3	20	50	13
	Sensititre				6	33	35	10	2
Ciprofloxacin	MIC	≤0.12	0.25	0.5	1	2	4	8	16	>16				54	67	56.5-76.0
	Reference				5	8	14	19	24	16
	Sensititre					4	8	14	21	39
Clarithromycin	MIC	≤0.06	0.12	0.25	0.5	1	2	4	8	16	32	64	>64	74	79	69.2-86.3
	Reference				21^a)	30	23	8	4
	Sensititre				2	25	45	12	2
Doxycycline	MIC	≤0.12	0.25	0.5	1	2	4	8	16	32	>32			24	63	52.4-72.4
	Reference							7	10	23	46
	Sensititre							8	19	59^b)
Ethambutol	MIC	≤0.5	1	2	4	8	16	32	>32					80	98	92.1-99.5
	Reference			2	16	34	27	5	2
	Sensititre		1	3	30	22	24	6^b)
Linezolid	MIC	≤1	1	2	4	8	16	32	64	>64				86	92	84.3-96.1
	Reference				1	13	28	35	9
	Sensititre				1	8	32	38	5	2
Moxifloxacin	MIC	≤0.12	0.25	0.5	1	2	4	8	>8					85	92	84.2-96.1
	Reference		2	5	9	24	43	3
	Sensititre			4	5	22	40	12	3
TMP-SMX	MIC	≤0.12/2.38	0.25/4.75	0.5/9.5	1/19	2/38	4/76	8/152	16/304	32/608				86	34	24.9-44.5
	Reference					3	32	28	22	1
	Sensititre	1	4	7	23	31	18	2

^a)≤ 0.5; ^b)>16.
Abbreviations: MIC, minimum inhibitory concentration; CI, confidence interval; EA, essential agreement; TMP-SMX, trimethoprim/sulfamethoxazole.