Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Weeks in Review

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Indexed in KCI, KoreaMed, Synapse, DOAJ
Open Access, Peer Reviewed
pISSN 2288-0585 eISSN 2288-6850

Search Results for: Chang Hyun Kim

Evaluation of Diagnostic Performance of Three Real-Time PCR Assays for the Detection of Mycobacteria Species

Original article Sang-wook Kim1*, Young-Hee Park2*, Young Jin Ko1,3, Yoon Ho Kim2, Chang Hyun Kim2, Chae Seung Lim1 Department of Laboratory Medicine, 1Korea University College of Medicine, Seoul, 2Korea University Medical Center Guro Hospital, Seoul, 3Department of Laboratory Medicine, College of Medicine, Chosun University, Gwangju, Korea *These authors contributed equally to this work. Corresponding to Young Jin Ko, E-mail: yjko@chosun.ac.kr Ann Clin Microbiol 2020;23(2):93-104. https://doi.org/10.5145/ACM.2020.23.2.6Received on 19 November 2019, Revised on 29 December 2019, Accepted on 29 December 2019, Published on 20 June 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Background: The disease burden caused by Mycobacterium tuberculosis (MTB) complex continues to decrease in most countries. However, the diseases caused by the nontuberculous mycobacteria (NTM) become a public health problem. This study aimed to compare the diagnostic accuracy of three real-time PCR assays: AdvanSure TB/NTM real-time PCR kit (AdvanSure; LG Chem., Korea), Genedia MTB/NTM detection kit (Genedia; Green Cross

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Prevalence and molecular characteristics of β-lactam resistance in non-typeable Haemophilus influenzae isolates in Korea

Original article Eun-Young Kim1, Yeon Chan Choi1, Hyeon Jin Choi1, Si Hyun Kim2, Jihyun Cho3, Seok Hoon Jeong4, Dokyun Kim4, Hyun Soo Kim5, Soo Hyun Kim6, Young Ah Kim7, Young Ree Kim8, Nam Hee Ryoo9, Jong Hee Shin6, Kyeong Seob Shin10, Young Uh11, Jeong Hwan Shin1 1Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea2Department of Biomedical Laboratory Science, Inje University, Gimhae, Korea.3Department of Laboratory Medicine, Wonkwang University Medical School, Iksan, Korea4Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea5Department of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea6Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea7Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea8Department of Laboratory Medicine, Jeju National University College of Medicine, Jeju, Korea9Department of Laboratory Medicine, Keimyung University School

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Principles and clinical applications of interferon-gamma release assays in latent tuberculosis diagnosis

Review article Ha-eun Cho1, Young Jin Kim2 1Department of Laboratory Medicine, Kyung Hee University Hospital, Seoul, Korea2Department of Laboratory Medicine, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, Korea Correspondence to Young Jin Kim, E-mail: khmclab@gmail.com Ann Clin Microbiol 2025;28(3):17. https://doi.org/10.5145/ACM.2025.28.3.6Received on 7 July 2025, Revised on 4 September 2025, Accepted on 4 September 2025, Published on 20 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Latent tuberculosis (TB) refers to a state in which an individual is infected with Mycobacterium tuberculosis but shows no clinical symptoms. The World Health Organization estimates that 23% of the global population has latent TB, which poses a significant public health challenge owing to the risk of progression to active TB. Diagnosis of latent TB involves tests, such as the

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Complete genome analysis of representative methicillin-resistant Staphylococcus aureus clinical strains prevalent in Korea during 2014-2017

Original article Harshad Lade1*, Tae-Im Kim1*, Jung-Min Kim1, Yong-Kyun Kim2, Kibum Jeon3, Hyun Soo Kim4, Han-Sung Kim5, Wonkeun Song6, Jae-Seok Kim1 1Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea2Department of Laboratory Medicine, Sahmyook Medical Center, Seoul, Korea3Department of Laboratory Medicine, Hallym University College of Medicine, Hangang Sacred Heart Hospital, Seoul, Korea4Department of Laboratory Medicine, Hallym University College of Medicine, Dongtan Sacred Heart Hospital, Hwaseong, Korea5Department of Laboratory Medicine, Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea6Department of Laboratory Medicine, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Korea *These authors contributed equally to this work. Correspondence to Jae-Seok Kim, E-mail: jaeseok@kdh.or.kr Ann Clin Microbiol 2025;28(3):15. https://doi.org/10.5145/ACM.2025.28.3.4Received on 23 May 2025, Revised on 20 June 2025, Accepted on 30 June 2025, Published on 10 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which

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Current status of mycobacterial identification in clinical laboratories in Korea

Review article Si Hyun Kim1, Jeong Hwan Shin2 1Department of Biomedical Laboratory Science, Inje University, Gimhae, Korea2Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea Correspondence to Jeong Hwan Shin E-mail: jhsmile@paik.ac.kr Ann Clin Microbiol 2025;28(3):16. https://doi.org/10.5145/ACM.2025.28.3.5Received on 30 June 2025, Revised on 30 July 2025, Accepted on 1 August 2025, Published on 11 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Accurate identification of the Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM) is crucial for effective patient management. With declining tuberculosis and rising NTM infections in South Korea, rapid diagnostics are essential. This review provides a comprehensive overview of current diagnostic methods for mycobacterial identification used in Korean clinical laboratories. The field has shifted from conventional methods, such as

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Evaluation of VITEK 2 system and VITEK MS system for the identification of Haemophilus species: a diagnostic accuracy study

Original article Yeon Chan Choi1*, Eun-Young Kim1*, Hyun Jin Choi1, Si Hyun Kim2, Eunkyoung You1, Ja Young Lee1, Jihyun Cho3, Seok Hoon Jeong4, Dokyun Kim4, Hyun Soo Kim5, Soo Hyun Kim6, Young Ah Kim7, Young Ree Kim8, Nam Hee Ryoo9, Jong Hee Shin10, Kyeong Seob Shin11, Young Uh12, Jeong Hwan Shin1 1Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea2Department of Biomedical Laboratory Science, Inje University, Gimhae, Korea3Department of Laboratory Medicine, Wonkwang University Medical School, Iksan, Korea4Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea5Department of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea6Department of Microbiology and Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea7Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea8Department of Laboratory Medicine, Jeju National University College of Medicine, Jeju,

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Isolation frequency and antimicrobial susceptibilities of Bacillus species in a tertiary care hospital in Korea in the past four years (2020–2024): a retrospective surveillance study

Original article Kwangjin Ahn1, Hyunju Choi1, Taesic Lee2, Young Uh1 1Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea2Department of Family Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea Correspondence to Young Uh, E-mail: u931018@yonsei.ac.kr Ann Clin Microbiol 2025;28(2):7. https://doi.org/10.5145/ACM.2025.28.2.1Received on 4 March 2025, Revised on 7 April 2025, Accepted on 14 April 2025, Published on 19 May 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: Identifying Bacillus spp. and performing antimicrobial susceptibility testing (AST) is challenging because of their diversity and limited clinical laboratory resources. We investigated the isolation frequency and antimicrobial susceptibility of Bacillus spp. over a 4-year period. Methods: Bacillus isolates collected between 2020 and 2024 were identified using matrixassisted laser desorption ionization-time of flight mass spectrometry, and AST was performed using

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A survey on laboratory capacity, testing practices, and management during COVID-19 pandemic response in Korea: a cross-sectional survey study

Original article Changseung Liu1, Daewon Kim2, Jung-Hyun Byun3, Jeonghyun Chang4, Sungjin Jo5, Heungsup Sung6 1Department of Laboratory Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea2Department of Laboratory Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea3Department of Laboratory Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea4Department of Laboratory Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea5Department of Laboratory Medicine, Eunpyeong St. Mary’s Hospital, Catholic University College of Medicine, Seoul, Korea6Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Correspondence to Heungsup Sung, E-mail: sung@amc.seoul.kr Ann Clin Microbiol 2025;28(1):5. https://doi.org/10.5145/ACM.2025.28.1.5Received on 28 February 2024, Revised on 10 March 2025, Accepted on 11 March 2025, Published on 20 March 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)

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Current epidemiology and implication for microbiological diagnosis of cryptococcal infections in Korea

Review article Myeong Hee Kim Department of Laboratory Medicine, Kyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong, Seoul, Korea Corresponding to Myeong Hee Kim, E-mail: meikim96@hanmail.net Ann Clin Microbiol 2024;27(4):257-265. https://doi.org/10.5145/ACM.2024.27.4.5Received on 7 October 2024, Revised on 12 November 2024, Accepted on 14 November 2024, Published on 20 December 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Cryptococcosis is a major invasive fungal infection affecting both immunocompromised and immunocompetent hosts worldwide and is mainly caused by Cryptococcus neoformans and Cryptococcus gattii. C. neoformans accounts for 90% of all infections and primarily causes central nervous system infections. Although C. gattii is primarily found in tropical and subtropical regions, infections have recently been reported in temperate areas such as Korea. Genetic studies in Korea indicated that most

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A Case of Prosthetic Valve Endocarditis with Cerebral Hemorrhage Caused by Rothia mucilaginosa

Case report Yeo-Jin Song1*, Bongyoung Kim1*, Young-eun Kim2, Yangsoon Lee2, Hyunjoo Pai1 1Department of Internal Medicine, 2Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea *These authors contributed equally to this work. Corresponding to Hyunjoo Pai, E-mail: paihj@hanyang.ac.kr Ann Clin Microbiol 2020;23(4):211-216. https://doi.org/10.5145/ACM.2020.23.4.6Received on 19 February 2020, Revised on 10 April 2020, Accepted on 10 April 2020, Published on 20 December 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Rothia spp. are aerobic, gram-positive cocci belonging to the family Micrococcaceae, and are a part of the normal microbial flora of the human oropharynx and upper respiratory tract. We present the first case of the prosthetic valve endocarditis with cerebral hemorrhage caused by Rothia mucilaginosa in South Korea. A 65-year-old man with a prosthetic aortic valve visited the outpatient clinic with a complaint of fever. R. mucilaginosa was identified in one among four sets of blood culture bottles obtained

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