Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

6

Weeks in Review

4

Weeks to Publication
Indexed in KCI, KoreaMed, Synapse, DOAJ
Open Access, Peer Reviewed
pISSN 2288-0585 eISSN 2288-6850

Search Results for: Ea Wha Kang

Prevalence and molecular characteristics of β-lactam resistance in non-typeable Haemophilus influenzae isolates in Korea

Original article Eun-Young Kim1, Yeon Chan Choi1, Hyeon Jin Choi1, Si Hyun Kim2, Jihyun Cho3, Seok Hoon Jeong4, Dokyun Kim4, Hyun Soo Kim5, Soo Hyun Kim6, Young Ah Kim7, Young Ree Kim8, Nam Hee Ryoo9, Jong Hee Shin6, Kyeong Seob Shin10, Young Uh11, Jeong Hwan Shin1 1Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea2Department of Biomedical Laboratory Science, Inje University, Gimhae, Korea.3Department of Laboratory Medicine, Wonkwang University Medical School, Iksan, Korea4Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea5Department of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, Korea6Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea7Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea8Department of Laboratory Medicine, Jeju National University College of Medicine, Jeju, Korea9Department of Laboratory Medicine, Keimyung University School

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Principles and clinical applications of interferon-gamma release assays in latent tuberculosis diagnosis

Review article Ha-eun Cho1, Young Jin Kim2 1Department of Laboratory Medicine, Kyung Hee University Hospital, Seoul, Korea2Department of Laboratory Medicine, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, Korea Correspondence to Young Jin Kim, E-mail: khmclab@gmail.com Ann Clin Microbiol 2025;28(3):17. https://doi.org/10.5145/ACM.2025.28.3.6Received on 7 July 2025, Revised on 4 September 2025, Accepted on 4 September 2025, Published on 20 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Latent tuberculosis (TB) refers to a state in which an individual is infected with Mycobacterium tuberculosis but shows no clinical symptoms. The World Health Organization estimates that 23% of the global population has latent TB, which poses a significant public health challenge owing to the risk of progression to active TB. Diagnosis of latent TB involves tests, such as the

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Current status of mycobacterial identification in clinical laboratories in Korea

Review article Si Hyun Kim1, Jeong Hwan Shin2 1Department of Biomedical Laboratory Science, Inje University, Gimhae, Korea2Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, Korea Correspondence to Jeong Hwan Shin E-mail: jhsmile@paik.ac.kr Ann Clin Microbiol 2025;28(3):16. https://doi.org/10.5145/ACM.2025.28.3.5Received on 30 June 2025, Revised on 30 July 2025, Accepted on 1 August 2025, Published on 11 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Accurate identification of the Mycobacterium tuberculosis complex (MTBC) and nontuberculous mycobacteria (NTM) is crucial for effective patient management. With declining tuberculosis and rising NTM infections in South Korea, rapid diagnostics are essential. This review provides a comprehensive overview of current diagnostic methods for mycobacterial identification used in Korean clinical laboratories. The field has shifted from conventional methods, such as

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Current epidemiology and implication for microbiological diagnosis of cryptococcal infections in Korea

Review article Myeong Hee Kim Department of Laboratory Medicine, Kyung Hee University College of Medicine and Kyung Hee University Hospital at Gangdong, Seoul, Korea Corresponding to Myeong Hee Kim, E-mail: meikim96@hanmail.net Ann Clin Microbiol 2024;27(4):257-265. https://doi.org/10.5145/ACM.2024.27.4.5Received on 7 October 2024, Revised on 12 November 2024, Accepted on 14 November 2024, Published on 20 December 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Cryptococcosis is a major invasive fungal infection affecting both immunocompromised and immunocompetent hosts worldwide and is mainly caused by Cryptococcus neoformans and Cryptococcus gattii. C. neoformans accounts for 90% of all infections and primarily causes central nervous system infections. Although C. gattii is primarily found in tropical and subtropical regions, infections have recently been reported in temperate areas such as Korea. Genetic studies in Korea indicated that most

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Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis

Original article Young Ah Kim1, Ea Wha Kang2, Hye Su Moon4, Daewon Kim3,4, Dongeun Yong3,4 1Department of Laboratory Medicine, 2Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, 3Department of Laboratory Medicine, 4Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea Corresponding to Dongeun Yong, E-mail: deyong@yuhs.ac Ann Clin Microbiol 2020;23(1):1-10. https://doi.org/10.5145/ACM.2020.23.1.1Received on 16 May 2019, Revised on 30 October 2019, Accepted on 26 November 2019, Published on 20 March 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Background: 16S rRNA gene-targeted next-generation sequencing (NGS) can detect microorganisms in a comprehensive reference database. To date, NGS has been successfully applied to samples such as urine, blood, and synovial fluid. However, there is no data for continuous ambulatory peritoneal dialysis (CAPD) fluid. The purpose of this study was to evaluate the clinical usefulness of microbiome analysis of CAPD fluids for the diagnosis of CAPD peritonitis. Methods:

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Anisakidosis in humans and animals and detection of anisakid larvae in fish and cephalopods in Korea: a literature review (1971-2022)

Review article Jong-Yil Chai1, Woon-Mok Sohn2, Bong-Kwang Jung3 1Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Seoul2Department of Parasitology and Tropical Medicine, Gyeongsang National University College of Medicine, Jinju;3MediCheck Research Institute, Korea Association of Health Promotion, Seoul, Korea Corresponding to Jong-Yil Chai, E-mail: cjy@snu.ac.kr Ann Clin Microbiol 2024;27(2):93-130. https://doi.org/10.5145/ACM.2024.27.2.6Received on 3 April 2024, Revised on 23 April 2024, Accepted on 29 April 2024, Published on 20 June 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Human anisakiasis (or anisakidosis) is a disease caused by the ingestion of marine fish or cephalopods infected with anisakid nematode larvae of the genera Anisakis, Pseudoterranova, Contracaecum, and Hysterothylacium. Anisakiasis is a clinically important disease that often manifests as an acute abdominal syndrome requiring emergency medical attention and care. In Korea, at

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Molecular Epidemiology of Methicillin-resistant Staphylococcus aureus Outbreak by Plasmid Restriction Analysis

Original article PDF Mi Ae Lee, M.D., Eun Sook Kang, M.D., Ki Sook Hong, M.D. and Wha Soon Chung, M.D. Department of Clinical Pathology, College of Medicine, Ewha Womans University Hospital, Seoul, Korea Corresponding to Mi Ae Lee, E-mail: miae@mm.ewha.ac.kr Ann Clin Microbiol 1999;2(2):125-130.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Methicillin-resistant Staphylococcus aureus (MRSA) continues to be a major cause of nosocomial infection and a molecular typing is necessary for proper epidemiologic investigations of sources and modes of spread in an outbreak. An nosocomial outbreak of MRSA in a neonatal intensive care unit at Ewha Womans University Mokdong Hospital was suspected. To investigate the clonality of isolates and control the spread of nosocomial outbreak, we performed plasmid restriction analysis of MRSA isolates from patients and medical staffs. Methods: We studied 7 MRSA strains (umbilicus 4, blood 1, urine 1 and pus 1) from patients in a neonatal intensive care unit

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Multicenter Study for the Frequency of 23S rRNA Point Mutations Associated with Clarithromycin Resistance in Helicobacter pylori in Korea

Original article PDF Hae Kyung Lee1, Hiun Suk Chae2, Jung Oak Kang3, Mi-Kyung Lee4, Heungsup Sung5, Mi-Na Kim5, Jongwook Lee6, Miae Lee7, Ki-Nam Shim8 Departments of 1Laboratory Medicine, 2Internal Medicine, The Catholic University of Korea College of Medicine, 3Department of Laboratory Medicine, Hanyang University College of Medicine, 4Department of Laboratory Medicine, Chung-Ang University College of Medicine, 5Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, 6Hanaro Medical Foundation, Departments of 7Laboratory Medicine, 8Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea Corresponding to Miae Lee, E-mail: miae@ewha.ac.kr Ann Clin Microbiol 2008;11(2):84-89.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Clarithromycin resistance in Helicobacter pylori is a major cause of eradication therapy failure. The objective of this study was to determine the frequency and type of mutations in the 23S rRNA gene in Korea, which are associated with clarithromycin resistance.  Methods: From January 2008 to March 2008, 353 gastric biopsy specimens were collected from five university

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First Report of Roseomonas aerofrigidensis Isolated from the Peritoneal Fluid of a Gastric Cancer Patient

Case report Eris Jang1, So Min Kim2, Junhyup Song2, Le Phuong Nguyen2,3, Hyukmin Lee2 1Sprayberry High School, Marietta, USA, 2Department of Laboratory Medicine and Research Institute of Bacterial Resistance, 3Brain Korea 21 plus Program for Medical Science, Yonsei University College of Medicine, Seoul, Korea Corresponding to Junhyup Song, E-mail: llive@yuhs.ac Ann Clin Microbiol 2021;24(2):61-65. https://doi.org/10.5145/ACM.2021.24.2.4Received on 20 April 2021, Revised on 20 April 2021, Accepted on 20 April 2021, Published on 20 June 2021.Copyright © Korean Society of Clinical Microbiology. Abstract Roseomonas aerofrigidensis is a gram-negative, strictly aerobic, non-motile bacterium, which was first isolated in 2017 in South Korea. We present the first report of the isolation of R. aerofrigidensis from the peritoneal fluid of a 38-year-old woman with a history of metastatic gastric cancer with peritoneal carcinomatosis. The isolate was resistant to cotrimoxazole. Further research on clinical and microbiological responses to several antibiotics are warranted. Keywords Gastric Cancer Patient,

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Prevalence of Helicobacter pylori infection and clarithromycin resistance rate from 2015 to 2018 in Korea: a repeated cross-sectional study

Original article Sunkyung Jung1, Mi-Na Kim2, Dongeun Yong3, Miae Lee4, Jongwook Lee5, Hae Kyung Lee6, Mi-Kyung Lee7, Helicobacter Study Group 1Department of Laboratory Medicine, Seegene Medical Foundation, Seoul, 2Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, 3Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, 4Department of Laboratory Medicine, Ewha Womans University Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, 5Department of Laboratory Medicine, Konyang University Hospital, Daejeon, 6Departments of Laboratory Medicine, College of Medicine, The Catholic University of Korea, Uijeongbu, 7Department of Laboratory Medicine, Chung-Ang University Hospital, Chung-Ang University College of Medicine, Seoul, Korea Corresponding to Mi-Kyung Lee, E-mail: cpworld@cau.ac.kr Ann Clin Microbiol 2024;27(1):19-30. https://doi.org/10.5145/ACM.2024.27.1.4The title has been changed from “Prevalence of Helicobacter pylori infection and clarithromycin resistance rate from 2015 to 2018 using the laboratory information system of the Seegene Medical Foundation in Korea: a repeated cross-sectional study”.Received on 23

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