Original article PDF Jeong Hwan Shin1,5, Hye Ran Kim1, Hi Ryune Lee1, Jae Il Chung2, Kweonsik Min2,5, Chi Sook Moon3, Seong Mi Ryu4, and Jeong Nyeo Lee1,5 Departments of Laboratory Medicine1, Urology2, and Internal Medicine3, College of Medicine, Paik Institute for Clinical Research5, Inje University, Infection Control Committee4, Inje University Busan Paik Hospital, Busan, Korea Corresponding to Jeong Hwan Shin, E-mail: jhsmile@inje.ac.kr Ann Clin Microbiol 2005;8(2):142-147.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Resistant organisms are now a growing and frequent problem in community-acquired infections. There is little information on the etiology and antimicrobial susceptibility patterns of community-acquired urinary tract infection (CA-UTI) at a tertiary-care hospital. Methods: We evaluated the distribution of etiological organisms with their antimicrobial susceptibility patterns of CA-UTI in the patients visiting a tertiary-care hospital during the period of three years from 2001 through 2003. Results: In total, 1,753 bacterial isolates yielded a significant growth as

Original article PDF Jongwook Lee1*, Sun Moon Kim2, Euyi Hyeog Im2, Young Woo Choi2, Yoon Mee Kim3 , Pum Soo Kim4, and Jae Hag Lee5 Departments of Laboratory medicine1, Internal Medicine2, and Pathology3, Keonyang University Hospital, Daejeon; Department of Internal Medicine4, Inha University Hospital, Incheon; Department of Food and Nutrition5, Seoil College, Seoul, Korea Corresponding to Jongwook Lee, E-mail: lee4@kyuh.co.kr Ann Clin Microbiol 2005;8(1):47-50.Copyright © Korean Society of Clinical Microbiology. Abstract Background: The most commonly used regimen for the eradication of Helicobacter pylori is combination of a proton pump inhibitor, clarithromycin, and two other antibiotics, metronidazole and amoxicillin. The increase in resistance to antibiotics seems to result in a decrease in eradication efficacy for H. pylori. We investigated the prevalence of antibiotic resistance in H. pylori isolated in Daejeon area. Methods: A total of 31 clinical isolates of H. pylori were collected from the patients who underwent upper gastrointestinal endoscopy in Keonyang University Hospital during the period from

Original article PDF Hye Ryong Oh1, Sook Jin Jang1,2, Feng Nan Yu1,2, Geon Park1, Xue Min Li2, Sung Heui Shin2, Won Yong Kim3, Dae Soo Moon1, Young Jin Park1 1Departments of Laboratory Medicine, 2Research Center for Resistant Cells, Chosun University Medical School, Gwangju; 3Department of Microbiology, Chungang University Medical School, Seoul, Korea Corresponding to Sook Jin Jang, E-mail: sjbjang@chosun.ac.kr Ann Clin Microbiol 2007;10(2):128-134.Copyright © Korean Society of Clinical Microbiology. Abstract Background: The incidence of infections with imipenem-resistant Acinetobacter baumannii (IRAB) and Pseudomonas aeruginosa (IRPA) is increasing worldwide, and recent molecular studies indicate that the prevalence of carbapenemases is increasing in various parts of the world. However, few long-term longitudinal studies have assessed the prevalence of IRAB- and IRPA-derived carbapenemases and integrases in a hospital setting in Korea. Methods: The carbapenemase genes (blaOXA-23, blaOXA-24, blaOXA-58, blaIMP-1, blaVIM-2, blaSIM-1, blaSPM-1) and integrase genes (intI1, intI2, intI3) produced by 46 IRAB strains and 51 IRPA strains collected at Chosun University Hospital between 2003 and 2006

Original article PDF Ji-Hyun Cho1,2,3, Hye-Soo Lee4, Key-Earn Lee1,2, Do-Sim Park1,2,3, Young-Jin Lee1,2,3, Hyung-Bae Moon2,3,5, Chang-Soo Choi2,3,6, Eun-Young Cho2,3,6, Haak-Cheoul Kim2,3,6 Departments of 1Laboratory Medicine, 5Pathology and 6Internal Medicine, 2Institute of Wonkwang Medical Science, 3Wonkwang Clinical Medicine Research Center, Wonkwang University College of Medicine, Iksan; 4Department of Laboratory Medicine, Chonbuk National University College of Medicine, Jeonju, Korea Corresponding to Haak-Cheoul Kim, E-mail: kimpb@wonkwang.ac.kr Ann Clin Microbiol 2007;10(1):25-31.Copyright © Korean Society of Clinical Microbiology. Abstract Background: As oral antiviral treatment for chronic hepatitis B increases, quantitation of viral load has become an essential test for HBV management, and assays using real-time PCR principles have been introduced recently. Methods: We analysed the analytical performance (precision, linear range, and sensitivity) of RealArt HBV LC PCR Reagents (Artus GmbH, Hamburg, Germany), its correlation with COBAS AMPLICOR HBV MONITOR Test (Roche Diagnostics, Mannheim, Germany), and distribution of viral load in the patients’ sera according to antiviral treatment and presence of HBeAg.

Case report PDF Hye Ryong Oh,1 Young Sook Kim2, Sook Jin Jang1,3, Xue Min Li3, Won Yong Kim4, Geon Park1, Dae Soo Moon1, Young Jin Park1 Departments of 1Laboratory Medicine, 2Radiology, and 3Research Center for Resistant Cells, Chosun University Medical School, Gwangju, 4Department of Microbiology, Chungang University Medical, Seoul, Korea Corresponding to Young Sook Kim, E-mail: yshkim@chosun.ac.kr Ann Clin Microbiol 2008;11(2):136-140.Copyright © Korean Society of Clinical Microbiology. Abstract Nocardia cyriacigeorgica is an aerobic gram-positive rod that has mostly been reported as an opportunistic pathogen. Since molecular methodologies were introduced to identify species, infections caused by N. cyriacigeorgica have been reported. The patient was a 51-year-old woman with aplastic anemia, systemic lupus erythematosus, and disseminated tuberculosis, who was admitted to Chosun University Hospital with a history of fever and productive cough. During her hospitalization, sputum cultures were taken and a bacterium suspicious of acitinomycetes grew five times. It was a gram-positive rod that was also partially acid-fast on modified Kinyoun

Original article PDF Hye Ryong Oh1, Dae Soo Moon2, Sook Jin Jang1,2, Xue Min Li2, Dong Min Kim3, Sang Gi Park4, Geon Park1, Young Jin Park2 Departments of 1Laboratory Medicine, 3Internal Medicine, 4Pediatrics, and 2Research Center for Resistant Cells, College of Medicine, Chosun University, Gwangju, Korea Corresponding to Dae Soo Moon, E-mail: dsmoon@chosun.ac.kr Ann Clin Microbiol 2008;11(2):123-128.Copyright © Korean Society of Clinical Microbiology. Abstract Background: In July 2007, three neonates in the neonatal intensive care unit (NICU) of Chosun University Hospital expired due to Escherichia coli sepsis. An E. coli outbreak was suspected.  Methods: To investigate the outbreak, environmental cultures were taken from NICU. We performed repetitive extragenic palindromic (rep)-PCR to compare genotypes of the three isolates from the cases and one environmental strain of E. coli. A case-control study was done in order to identify risk factors for the infection.  Results: In July 2007, the attack rate of E. coli was 11.1%, which was higher than the basal rate. All

Original article PDF Ja Young Lee1, Jeong Hwan Shin1,2, Hyun-Kyung Lee3, Seong-Mi Yu5, Eun Hee Park6, Hee Ryune Lee1, Jae Hyen Kim1, Hye Ran Kim1, Chi Sook Moon3, Young Jae Kim4, Jeong Nyeo Lee1,2 1Department of Laboratory Medicine, 2Paik Institute for Clinical Research, Departments of 3Internal Medicine and 4Anesthesiology, College of Medicine, Inje University, Busan; 5Department of Nursing, Gwangju Health College, Gwangju; 6Busan Metropolitan City Institute of Health and Environment, Busan, Korea Corresponding to Jeong Hwan Shin, E-mail: jhsmile@inje.ac.kr Ann Clin Microbiol 2008;11(1):29-34.Copyright © Korean Society of Clinical Microbiology. Abstract Background: We noticed a sudden increase in the isolation of Klebsiella oxytoca from bronchial washing specimens during May to June 2006. An epidemiological investigation was conducted to identify the cause of the outbreak and to implement appropriate infection control measures.  Methods: A total of 18 isolates of K. oxytoca were found. The 14 bronchial washing specimens that yielded K. oxytoca were taken in the outpatient bronchoscopy suite, and the other 4

Original article PDF Soo Jin Yoo1, Choong-Hee Noh2,3, Hyeon Mi Yoo2, Won Chang Shin4, Soo Jeon Choi4, Baek-Nam Kim4, Chang Keun Kim5, Myoung-Jae Chey5, Kyunam Kim6, Sang-Lae Lee7, Eun-Young Kuak1, Bo-Moon Shin1,2 Departments of 1Laboratory Medicine, 2Infection Control Office, 3Urology, 4Internal Medicine, 5Pediatrics, 6Family Medicine, and 7Emergency Medicine, Sanggye Paik Hospital, Inje University College of Medicine, Seoul, Korea Corresponding to Bo-Moon Shin, E-mail: bmshin@unitel.co.kr Ann Clin Microbiol 2010;13(3):103-108. https://doi.org/10.5145/KJCM.2010.13.3.103Copyright © Korean Society of Clinical Microbiology. Abstract Background: The aim of this study is to clarify the epidemiology of swine-origin influenza A (H1N1) virus 2009 (S-OIV) during the first month of outbreak at one of influenza clinic in Seoul, Korea.  Methods: We documented the epidemiologic and clinical features of S-OIV-confirmed cases who visited a university hospital in Northeastern Seoul between August 21 and September 20, 2009. Nasopharyngeal swab of patients with acute febrile respiratory illnesses were evaluated with rapid influenza antigen