“Hyukmin Lee”에 대한 검색 결과 – Annals of Clinical Microbiology

Whole-genome characterization of two azithromycin-resistant Neisseria gonorrhoeae ST1600 isolates from Busan, South Korea

Brief communication Changseung Liu1, Young Hee Seo2, Kyoung Ho Roh3, Hyukmin Lee2, Kyungwon Lee2,4 1Department of Laboratory Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea2Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea3Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, Korea4Seoul Clinical Laboratories Academy, Yongin, Korea Correspondence to Kyoung Ho Roh E-mail: director.roh@gmail.com Ann Clin Microbiol 2026;29(2):8. https://doi.org/10.5145/ACM.2026.29.2.8Received on 10 April 2026, Revised on 27 May 2026, Accepted on 7 June 2026, Published on 20 June 2026.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Azithromycin-resistant Neisseria gonorrhoeae poses a threat to the efficacy of gonorrhea treatment. We report the whole-genome characterization of two azithromycin-resistant N. gonorrhoeae ST1600 isolates collected in Busan, South Korea, in 2018

Evaluating the adequacy of intervals for repeat antimicrobial susceptibility testing

Original article Yu Jin Park1, Xinyi Lu2, Sunghyuk Kim1, Shinyoung Yoon1, Daewon Kim3, Ki Ho Hong1, Hyukmin Lee1, Dongeun Yong1,4 1Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea2Graduate School of Medicine, Yonsei University College of Medicine, Seoul, Korea3Department of Laboratory Medicine, Gachon University Gil Medical Center, Incheon, Korea4Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea Correspondence to Dongeun Yong E-mail: deyong@yuhs.ac Ann Clin Microbiol 2026;29(2):7. https://doi.org/10.5145/ACM.2026.29.2.7Received on 23 March 2026, Revised on 11 May 2026, Accepted on 26 May 2026, Published on 20 June 2026.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: The optimal frequency for repeat antimicrobial susceptibility testing (AST) of isolates of the same species remain undefined despite its importance in

Mock communities to assess biases in next-generation sequencing of bacterial species representation

Original article Younjee Hwang1,2*, Ju Yeong Kim1,3*, Se Il Kim4,5, Ji Yeon Sung1,6, Hye Su Moon1, Tai-Soon Yong3, Ki Ho Hong1, Hyukmin Lee1, Dongeun Yong1 1Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea2Brain Korea 21 PLUS Project for Medical Science, Yonsei University College of Medicine, Seoul, Korea3Department of Tropical Medicine, Institute of Tropical Medicine and Arthropods of Medical Importance Resource Bank, Yonsei University College of Medicine, Seoul, Korea4Division of Chemical and Medical Metrology, Center for Bioanalysis, Korea Research Institute of Standards and Science, Daejeon, Korea5Convergent Research Center for Emerging Virus Infection, Korea Research Institute of Chemical Technology, Daejeon, Korea6Roche Diagnostics Korea, Seoul, Korea*These authors contributed equally to this work. Correspondence to Dongeun Yong, E-mail: deyong@yuhs.ac Ann Clin Microbiol 2025;28(1):3. https://doi.org/10.5145/ACM.2025.28.1.3Received on 31 December 2024, Revised on 6 March 2025, Accepted on 10 March 2025, Published on 20 March 2025.Copyright © Korean

Performance of Modified-EUCAST Rapid Direct Antimicrobial Susceptibility Testing on Clinical Urine Samples

Original article Justin Mugiraneza1, Mijung Kwon2, Daewon Kim2, Sang-Guk Lee2, Hyukmin Lee2, Dongeun Yong2 1Department of Global Health Security, Yonsei University Graduate school of Public Health, Seoul, 2Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea Corresponding to Dongeun Yong, E-mail: deyong@yuhs.ac Ann Clin Microbiol 2020;23(3):125-134. https://doi.org/10.5145/ACM.2020.23.3.2Received on 28 January 2020, Revised on 27 March 2020, Accepted on 27 March 2020, Published on 20 September 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Background: The rapid antimicrobial susceptibility testing (AST) performed on urine samples would guide the adequate choice of antibiotics for obtaining better treatment outcomes in patients. Our study aimed to evaluate the performance of the modified-EUCAST (European Committee on Antimicrobial Susceptibility Testing) rapid direct AST on urine samples. Methods: From >2,000 urine samples, a total of 128 urine samples containing bacterial counts of ≥2 × 104 CFU/mL with a uniform

Detection of Toxin B Gene of Clostridium difficile by Polymerase Chain Reaction from Clinical Isolates

Original article PDF Hyukmin Lee, M.D., Young Ah Kim, M.D., Kwang Il Park, M.D., Kyungwon Lee, M.D. and Yunsop Chong, Ph.D. Department of Clinical Pathology and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea Corresponding to Kyungwon Lee Ann Clin Microbiol 1999;2(1):77-81.Copyright © Korean Society of Clinical Microbiology. Abstract Background：Clostridium difficile causes antibiotic-associated diarrhea or pseudomembranous colitis by producing of toxins in patients treated with antimicrobial agents. Stool cultures for C. difficile and tests for the presence of its toxin are the most widely used methods for the diagnosis of infection. The aim of this study was to determine the usefulness of polymerase chain reaction for the detection of toxin B gene from C. difficile isolates. Methods：In this study, 85 strains of C. difficile were used, which were isolated from stool specimens of patients with suspected antibiotic-associated diarrhea or pseudomembranous colitis from 1987 to 1994 using cefoxitin-cycloserine-fructose agar. DNA of the C. difficile isolates was

A Case of Bacteremia by Plesiomonas shigelloides

Case report PDF Hyukmin Lee, M.D., Kyungja Woo, M.T., Kyungwon Lee, M.D., Yunsop Chong, Ph.D., and Joo Hang Kim, M.D.* Departments of Clinical Pathology and Internal Medicine*, Yonsei University College of Medicine, Seoul, Korea Corresponding to Kyungwon Lee Ann Clin Microbiol 2000;3(2):137-141.Copyright © Korean Society of Clinical Microbiology. Abstract Plesiomonas shigelloides was isolated from blood culture of a 53-year-old man with fever, who had treatment history of gastrointestinal malignancy. The patient showed neither clinical features nor hematological finding which suggest bacteremia. Identification of the isolate was delayed because of its similar characteristics with Aeromonas spp. and other gram-negative bacilli. The isolate was misinterpreted as susceptible to ampicillin by the first disk diffusion test. It may not always easy to identify P. shigelloides by conventional tests and to determine its antimicrobial susceptibility accurately, as laboratorians rarely have experience with the organism and as the organism may show unusual inhibition pattern when tested by disk diffusion method

Comparison of Tn1546-like Elements in vanA Genotype Enterococcus gallinarum and E. faecalis or E. faecium

Original article PDF Hyukmin Lee1, Eun Mi Koh2, Myung Sook Kim2, Jong Hwa Yum2, Dongeun Yong2, Wee Gyo Lee3, Kyungwon Lee2, Yunsop Chong2 1Department of Laboratory Medicine, Kwandong University College of Medicine, Goyang; 2Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul; 3Department of Laboratory Medicine, Ajou University School of Medicine, Suwon, Korea Corresponding to Kyungwon Lee, E-mail: leekcp@yumc.yonsei.ac.kr Ann Clin Microbiol 2007;10(2):114-118.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Enterococcus gallinarum, an organism often found in the intestine, is intrinsically resistant to low level vancomycin, but some of them are highly resistant to vancomycin due to acquisition of vanA gene. We occasionally detected both vanA carrying E. gallinarum and E. faecalis or E. faecium in the same patients, suggesting transfer of the resistance gene from the latter. In this study, the structures of Tn1546-like elements in E. gallinarum, and E. faecalis or E. faecium from the same patients were compared to determine the clinical significance of the vanA genotype E. gallinarum isolates. Methods: Six

Antimicrobial Resistance of Clinically Important Bacteria Isolated from 12 Hospitals in Korea in 2005 and 2006

Original article PDF Hyukmin Lee1, Chang Ki Kim2, Jongwook Lee3, Sung-Hee Lee4, Ji Young Ahn5, Seong Geun Hong6, Yeon Jun Park7, Seok Hoon Jeong8, Eui-Chong Kim9, Wee Kyo Lee10, Young Uh11, Jong Hee Shin12, Tae Yeal Choi13, Hyo-Sun Kwak14, Kyungwon Lee2 Department of Laboratory Medicine, 1Kwandong University College of Medicine, Goyang; 2Yonsei University College of Medicine, Seoul; 3Keonyang University Medical College, Daejeon; 4Cheju Hanmaeum Hospital, Jeju; 5Sooncheonhyang University College of Medicine, Gumi; 6Pochon CHA University College of Medicine, Seongnam; 7 The Catholic University of Korea College of Medicine, Seoul; 8Kosin University College of Medicine, Busan; 9Seoul National University College of Medicine, Seoul; 10Ajou University College of Medicine, Suwon; 11Yonsei University Wonju College of Medicine, Wonju; 12Chonnam National Univeristy Medical School, Gwangju; 13Hanyang University College of Medicine, Seoul; 14Food Microbiology Division, Center for Food Safety Evaluation, Korea Food and Drug Administration, Seoul, Korea Corresponding to Kyungwon Lee, E-mail: leekcp@yumc.yonsei.ac.kr Ann Clin Microbiol 2007;10(1):59-69.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Emergence and spread of antimicrobial

Predicting phenotypic antimicrobial resistance in Escherichia coli isolates, using whole genome sequencing data

Original article Hyunsoo Kim1, Young Ah Kim2, Young Hee Seo3, Hyukmin Lee3,4, Kyungwon Lee3,4 1Department of Laboratory Medicine, National Police Hospital, Seoul, 2Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, 3Research Institute of Bacterial Resistance and Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, 4Seoul Clinical Laboratories, Yongin, Korea Corresponding to Young Ah Kim, E-mail: yakim@nhimc.or.kr Ann Clin Microbiol 2022;25(4):119-124. https://doi.org/10.5145/ACM.2022.25.4.2Received on 13 July 2022, Revised on 6 September 2022, Accepted on 8 September 2022, Published on 20 December 2022.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The application of genotypic antimicrobial sensitivity tests (ASTs) is dependent on the reliability of the predictions of phenotypic resistance. In this study,

Clinical usefulness of the QMAC-dRAST system for AmpC β-lactamase-producing Enterobacterales

Original article Heekang Choi1, Daewon Kim1,2, Mijung Kwon1, Jung-Hyun Byun3, Bonghwan Jin4, Ki-Ho Hong1, Hyukmin Lee1, Dongeun Yong1 1Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 2Department of Laboratory Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, 3Department of Laboratory Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, 4QuantaMatrix Inc., Seoul, Korea Corresponding to Daewon Kim, E-mail: fseraph85@gmail.com Ann Clin Microbiol 2022;25(4):109-118. https://doi.org/10.5145/ACM.2022.25.4.1Received on 1 July 2022, Revised on 7 September 2022, Accepted on 8 September 2022, Published on 20 December 2022.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: Rapid antimicrobial susceptibility testing (RAST) is important for the appropriate treatment

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