Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

6

Weeks in Review

4

Weeks to Publication
Indexed in KCI, KoreaMed, Synapse, DOAJ
Open Access, Peer Reviewed
pISSN 2288-0585 eISSN 2288-6850

Search Results for: Jeong Su Park

Pulmonary infection caused by Segniliparus rugosus in a patient without systemic immunodeficiency but with bronchiectasis: first identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with whole-genome confirmation

Letter to the editor Jaesoon Kim1,2*, Nakwon Kwak3,4*, Jee-Soo Lee1,2, Taek Soo Kim1,2, Moon-Woo Seong1,2, Jae Hyeon Park1 1Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea2Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea3Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Seoul National University Hospital, Seoul, Korea4Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea *These authors contributed equally to this work. Correspondence to Jae Hyeon Park, E-mail: bjack9@snu.ac.kr Ann Clin Microbiol 2026;29(1):2. https://doi.org/10.5145/ACM.2026.29.1.2Received on 1 January 2026, Revised on 15 January 2026, Accepted on 30 January 2026, Published on 27 February 2026.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Dear Editor, Segniliparus spp. are acid-fast, rapidly growing bacteria associated with pulmonary infections, particularly in patients with underlying lung disease.

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Whole-genome sequencing as the new framework of clinical microbiology and highlights in this issue

Editorial Hae-Sun Chung Department of Laboratory Medicine, Ewha Womans University College of Medicine, Seoul, Korea Correspondence to Hae-Sun Chung, E-mail: sunny0521.chung@ewha.ac.kr Ann Clin Microbiol 2025;28(4):27. https://doi.org/10.5145/ACM.2025.28.4.8Received on 16 December 2025, Revised on 18 December 2025, Accepted on 18 December 2025, Published on 20 December 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). The expanding role of whole-genome sequencing in clinical microbiology: A specially invited review Infectious diseases remain a leading cause of morbidity and mortality worldwide, and antimicrobial resistance (AMR) continues to erode the effectiveness of standard treatment pathways. Against this backdrop, whole-genome sequencing (WGS) has shifted from being a specialized research capability to a practical engine for clinical decision support, outbreak investigation, and pathogen surveillance. The review by the distinguished Japanese scholar Professor Takashi Takahashi [1], “Whole-genome sequencing applications for

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Drug susceptibility testing of Mycobacterium avium complex using the SLOMYCO test-system: a diagnostic accuracy study

Original article Jeong Su Park1*, Kyu-Hwa Hur2*, Woo Jin Shin1, Hyunji Kim1, Dong Woo Shin1, Kyoung Un Park1 1Department of Laboratory Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea2Department of Laboratory Medicine, Green Cross Laboratories, Yongin, Korea*These authors contributed equally to this work. Correspondence to Jeong Su Park, E-mail: mdmicrobe@gmail.com Ann Clin Microbiol 2025;28(4):24. https://doi.org/10.5145/ACM.2025.28.4.5Received on 12 November 2025, Revised on 10 December 2025, Accepted on 10 December 2025, Published on 20 December 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: Mycobacterium avium complex (MAC) is a major cause of pulmonary nontuberculous mycobacterial disease; however, treatment outcomes remain suboptimal. Phenotypic drug susceptibility testing (DST) is conditionally recommended; however, conventional broth microdilution is labor-intensive. The Sensititre SLOMYCO® panel offers a standardized platform for DST

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A multicenter study on antimicrobial resistance in bloodstream pathogens isolated in Korea: a survey study

Original article Jung-ah Kim1*, Sae Am Song2*, Sunjoo Kim3, Sunggyun Park4, Kwangsook Woo5, Yu Kyung Kim6 1Department of Laboratory Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea2Department of Laboratory Medicine, Inje University College of Medicine, Busan, Korea3Department of Laboratory Medicine, Gyeongsang National University College of Medicine, Jinju, Korea.4Departments of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea5Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea6Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea *These authors contributed equally to this work. Correspondence to Sunjoo Kim, E-mail: sjkim8239@hanmail.net Ann Clin Microbiol 2025;28(2):10. https://doi.org/10.5145/ACM.2025.28.2.4Received on 30 May 2025, Revised on 12 June 2025, Accepted on 12 June 2025, Published on 27 June 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: Bacterial antimicrobial resistance (AMR) is a major

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A survey on laboratory capacity, testing practices, and management during COVID-19 pandemic response in Korea: a cross-sectional survey study

Original article Changseung Liu1, Daewon Kim2, Jung-Hyun Byun3, Jeonghyun Chang4, Sungjin Jo5, Heungsup Sung6 1Department of Laboratory Medicine, Gangneung Asan Hospital, University of Ulsan College of Medicine, Gangneung, Korea2Department of Laboratory Medicine, Gil Medical Center, Gachon University College of Medicine, Incheon, Korea3Department of Laboratory Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, Korea4Department of Laboratory Medicine, Inje University Ilsan Paik Hospital, Goyang, Korea5Department of Laboratory Medicine, Eunpyeong St. Mary’s Hospital, Catholic University College of Medicine, Seoul, Korea6Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Correspondence to Heungsup Sung, E-mail: sung@amc.seoul.kr Ann Clin Microbiol 2025;28(1):5. https://doi.org/10.5145/ACM.2025.28.1.5Received on 28 February 2024, Revised on 10 March 2025, Accepted on 11 March 2025, Published on 20 March 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND)

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Seasonality and epidemiological trends in species distribution and antifungal susceptibility of Candida species isolated from various clinical specimens conducted during 2011–2022, Korea: a retrospective surveillance study

Original article Seo Young Hwang, Young Kwan Lim, Kye Won Choe, Young ho Choi, Mi-Kyung Lee Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea Corresponding to Mi-Kyung Lee, E-mail: cpworld@cau.ac.kr Ann Clin Microbiol 2024;27(3):185-196. https://doi.org/10.5145/ACM.2024.27.3.6Received on 2 February 2024, Revised on 8 September 2024, Accepted on 9 September 2024, Published on 20 September 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: As most Candida species cause opportunistic infections, it is helpful for patient care to determine species name of Candida spp. and their distribution in both sterile and non-sterile specimens. We aimed to investigate trends in the distribution of Candida species isolated from a hospital in Korea, along with their antifungal susceptibilities and seasonal variations. Methods: This study was conducted at the Chung-Ang University Hospital and included 8,760 different clinical specimens from

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Causes and Clinical Relevance of Inconclusive SARS-CoV-2 Real-Time Reverse Transcription-PCR Test Results

Original article Aram Kim, Heerah Lee, Kyu-Hwa Hur, Heungsup Sung, Mi-Na Kim Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Corresponding to Mi-Na Kim, E-mail: mnkim@amc.seoul.kr Ann Clin Microbiol 2020;23(4):191-199. https://doi.org/10.5145/ACM.2020.23.4.4Received on 23 August 2020, Revised on 28 Septenber 2020, Accepted on 13 October 2020, Published on 20 December 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Inconclusive SARS-CoV-2 real-time reverse transcription-PCR (rRT-PCR) test results, which are positive for one or more target genes but not all, are problematic in clinical laboratories. In this study, we aimed to investigate the cause and clinical relevance of such inconclusive results. Methods: rRT-PCR was performed using the Allplex 2019-nCoV assay kit (Seegene Inc., Korea) targeting the following three genes: E, RdRp, and N. For all inconclusive test results reported from March to June 2020, the frequency per kit, lot number, specimen type, cycle threshold (Ct)

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Serological diagnosis of tissue-invading parasites in Korea

Review article Min-Ho Choi Department of Parasitology and Tropical Medicine, Institute of Endemic Diseases, Seoul National University College of Medicine, Seoul, Korea Corresponding to Min-Ho Choi, E-mail: mhchoi@snu.ac.kr Ann Clin Microbiol 2024;27(2):81-91. https://doi.org/10.5145/ACM.2024.27.2.5Received on 17 May 2024, Revised on 20 May 2024, Accepted on 20 May 2024, Published on 20 June 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Although intestinal parasites are no longer considered a significant public health concern in Korea, tissue-invading parasites continue to pose clinical challenges. The diagnosis of tissue helminthiasis by recovering worms or larvae from tissues is invasive; therefore, serodiagnosis is widely used to diagnose infections caused by tissue-invading parasites. Among the serological tests, the enzyme-linked immunosorbent assay (ELISA) is the most commonly used, and various antigens, including crude antigens, excretory-secretory antigens of helminths,

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Identification, Antimicrobial Susceptibility and Epidemiology of Klebsiella species Isolated from Clinical Specimen

Original article PDF Young Uh*, Soon Deok Park, Jeong Seog Son*, Hyeun Gyeo Lee*, An Suk Jeoung*, Hyun Mi Cho*, and Kap Jun Yoon*, and Hyo Youl Kim Departments of Clinical Pathology* and Internal Medicine**, Yonsei University Wonju College of Medicine, Wonju, and Research Institute of Bacterial Resistance***, Yonsei University College of Medicine, Seoul, Korea Corresponding to Young Uh Ann Clin Microbiol 2000;3(2):99-110.Copyright © Korean Society of Clinical Microbiology. Abstract Background: In recent years, the incidence of extended-spectrum β-lactamase (ESBL) producing Klebsiella has been steadily increased, and the newer species K. planticola and K. terrigena, formerly regarded as nonpathogen, have been reported with astonishing frequency from human infectious processes by some investigators. The aim of this study is to elucidate the isolation rate and antimicrobial susceptibility of recent clinical Klebsiella isolates. Method: For the clinical Klebsiella isolates during the period of June 1999 to May 2000, isolation frequency of Klebsiella species by specimen, departments, age, and sex were analyzed. And antimicrobial susceptibilities

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Identification Results of Aerobic Gram-positive Bacteria Isolated from Blood Cultures Using BBL Crystal GP ID System

Original article PDF Young Uh, Gyu Yel Hwang, In Ho Jang, Hyeun Gyeo Lee, An Suk Jeoung, Soon Deok Park, Jeong Seog Son, and Kap Jun Yoon Department of Clinical Pathology, Yonsei University Wonju College of Medicine, Wonju, Korea Corresponding to Young Uh, E-mail: u931018@wonju.yonsei.ac.kr Ann Clin Microbiol 2001;4(1):22-27.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Although most of aerobic gram-positive bacilli have been considered to be contaminants, gram-positive bacilli should be identified to the species level if they are isolated from sterile body sites such as blood, and from adequately collected clinical specimens if they are the predominant organisms. However, identification of gram-positive bacilli are difficult due to the enormous diversity of these organisms and the small number of readily available commercial identification systems in clinical laboratories. Gram-positive bacilli and coccorods isolated from blood cultures were tested with BBL Crystal Gram-Positive (GP) Identification (ID) system in order to

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