Original article Seo Young Hwang, Young Kwan Lim, Kye Won Choe, Young ho Choi, Mi-Kyung Lee Department of Laboratory Medicine, Chung-Ang University College of Medicine, Seoul, Korea Corresponding to Mi-Kyung Lee, E-mail: cpworld@cau.ac.kr Ann Clin Microbiol 2024;27(3):185-196. https://doi.org/10.5145/ACM.2024.27.3.6Received on 2 February 2024, Revised on 8 September 2024, Accepted on 9 September 2024, Published on 20 September 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: As most Candida species cause opportunistic infections, it is helpful for patient care to determine species name of Candida spp. and their distribution in both sterile and non-sterile specimens. We aimed to investigate trends in the distribution of Candida species isolated from a hospital in Korea, along with their antifungal susceptibilities and seasonal variations. Methods: This study was conducted at the Chung-Ang University Hospital and included 8,760 different clinical specimens from

Original article Young-Suk Sohn1, Jung-Hyun Byun2, Young Ah Kim3, Dong-Chun Shin4, Kyungwon Lee1 1Department of Laboratory Medicine, Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 2Department of Laboratory Medicine, Gyeongsang National University Hospital, Gyeongsang National University College of Medicine, Jinju, 3Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, 4Department of Environmental Health Graduate School of Public Health, Yonsei University, Seoul, Korea Corresponding to Young Ah Kim, E-mail: yakim@nhimc.or.kr Ann Clin Microbiol 2020;23(1):33-43. https://doi.org/10.5145/ACM.2020.23.1.33Received on 8 July 2019, Revised on 23 August 2019, Accepted on 23 August 2019, Published on 20 March 2019.Copyright © Korean Society of Clinical Microbiology. Abstract Background: The weather has well-documented effects on infectious disease and reports suggest that summer peaks in the incidences of gram-negative bacterial infections among hospitalized patients. We evaluated how season and temperature changes affect bloodstream infection (BSI) incidences of major pathogens to understand BSI trends with

Original article Hyunmi Cho1, Jong-Bae Kim2, Young Uh1 1Department of Laboratory Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, 2Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Korea Corresponding to Young Uh, E-mail: u931018@yonsei.ac.kr Ann Clin Microbiol 2020;23(1):21-31. https://doi.org/10.5145/ACM.2020.23.1.21Received on 12 June 2019, Revised on 19 August 2019, Accepted on 19 August 2019, Published on 20 March 2019.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Rapid and accurate detection of Mycobacterium tuberculosis (MTB) is of primary importance for infection control and selection of anti-tuberculosis drugs. However, most clinical laboratories report MTB complex (MTC) without reporting MTB because MTC comprising MTB, Mycobacterium bovis, Mycobacterium africanum, Mycobacterium microti, Mycobacterium capraei and Mycobacterium pinnipedii have 99.9% similarity at the nucleotide level and identical 16S rRNA sequences. This study was conducted to analyze the species frequency of MTC isolates obtained from clinical specimen. Methods: Of

Original article PDF Young Uh, M.D., Jeong Seog Son, M.D., Gyu Yel Hwang, M.D., In Ho Jang, M.D., Kap Jun Yoon, M.D., and Dong Min Seo, M.D. Departments of Clinical Pathology and Medical Information Development, Yonsei University Wonju College of Medicine, Wonju, Korea Corresponding to Young Uh Ann Clin Microbiol 1998;1(1):82-96.Copyright © Korean Society of Clinical Microbiology. Abstract Background: In clinical microbiology the accurate and rapid identification of members of the family Enterobacteriaceae is essential for diagnostic and therapeutic purposes and for epidemiologic studies. Accuracy of identification system depends mainly on data base such as positive rate of biochemical reactions, relative frequency of occurrence of biotype, and isolation frequency of microorganisms. The purpose of this study was to analyze the isolation rate and biotype frequency of the family Enterobacteriaceae isolated from tertiary care hospital in Korea. Methods: Isolation frequency of the family Enterobacteriaceae isolated from clinical specimens during the period of January 1998 to June 1998

Original article PDF Yoon Hee Kang, M.D., Soo Jin Choi, M.D., Sang Hyun Hwang, M.D., Young Wook Cho, M.D., Duck-Hee Kim, M.T.*, Mi-Na Kim, M.D. and Chik Hyun Pai, M.D. Department of Clinical Pathology, University of Ulsan College of Medicine and Asan Medical Center, Seoul, Korea Corresponding to Mi-Na Kim Ann Clin Microbiol 1999;2(2):158-166.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Escherichia coli and Klebsiella pneumoniae resistant to 3rd generation cephalosporin have been reported with increasing frequency in tertiary-care hospital in Korea. MicroScan Neg Combo Panel Type 21 (Type 21) contains a 1 µg/mL cepfoxodime (POD) in addition to other screen wells containing ceftazidime, cefotaxime, ceftriaxone, and aztreonam, which are designed for detecting extended-spectrum β-lactamase (ESBL)-producing E. coli and Klebsiella species. We evaluated the Type 21 panel for its ability to detect ESBL. Methods: From November to December in 1998, 496 E. coli and 326 K. pneumoniae strains isolated from clinical specimens were tested with Type 21 panel. The isolates