Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Weeks in Review

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Indexed in KCI, KoreaMed, Synapse, DOAJ
Open Access, Peer Reviewed
pISSN 2288-0585 eISSN 2288-6850

Search Results for: Sung Hee Chung

A Case of Whole Genome Analysis of SARS-CoV-2 Using Oxford Nanopore MinION System

Case report Jae-Seok Kim, Sung Hee Chung, Jung-Min Kim, Hyun Soo Kim, Han-Sung Kim, Wonkeun Song Department of Laboratory Medicine, Hallym University College of Medicine, Seoul, Korea Corresponding to Jae-Seok Kim, E-mail:  jaeseok@hallym.ac.kr Ann Clin Microbiol 2021;24(4):135-140. https://doi.org/10.5145/ACM.2021.24.4.4Received on 28 June 2021, Revised on 27 September 2021, Accepted on 11 November 2021, Published on 20 December 2021.Copyright © Korean Society of Clinical Microbiology. Abstract The application of whole genome sequencing on SARS-CoV-2 viral genome is essential for our understanding of the molecular epidemiology and spread of viruses in the community. The portable whole genome sequencer MinION (Oxford Nanopore Technologies, ONT, UK) could be feasibly used in a clinical microbiology laboratory without the need of vast resources or stringent operating conditions. We used the MinION sequencer to analyze the viral genome sequence of one SARS-CoV-2 strain. In June 2020, nasopharyngeal specimen from one patient was subjected to whole-genome analysis using the

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Complete genome analysis of representative methicillin-resistant Staphylococcus aureus clinical strains prevalent in Korea during 2014-2017

Original article Harshad Lade1*, Tae-Im Kim1*, Jung-Min Kim1, Yong-Kyun Kim2, Kibum Jeon3, Hyun Soo Kim4, Han-Sung Kim5, Wonkeun Song6, Jae-Seok Kim1 1Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea2Department of Laboratory Medicine, Sahmyook Medical Center, Seoul, Korea3Department of Laboratory Medicine, Hallym University College of Medicine, Hangang Sacred Heart Hospital, Seoul, Korea4Department of Laboratory Medicine, Hallym University College of Medicine, Dongtan Sacred Heart Hospital, Hwaseong, Korea5Department of Laboratory Medicine, Hallym University College of Medicine, Hallym University Sacred Heart Hospital, Anyang, Korea6Department of Laboratory Medicine, Hallym University College of Medicine, Kangnam Sacred Heart Hospital, Seoul, Korea *These authors contributed equally to this work. Correspondence to Jae-Seok Kim, E-mail: jaeseok@kdh.or.kr Ann Clin Microbiol 2025;28(3):15. https://doi.org/10.5145/ACM.2025.28.3.4Received on 23 May 2025, Revised on 20 June 2025, Accepted on 30 June 2025, Published on 10 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which

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A multicenter study on antimicrobial resistance in bloodstream pathogens isolated in Korea: a survey study

Original article Jung-ah Kim1*, Sae Am Song2*, Sunjoo Kim3, Sunggyun Park4, Kwangsook Woo5, Yu Kyung Kim6 1Department of Laboratory Medicine, Soonchunhyang University Seoul Hospital, Seoul, Korea2Department of Laboratory Medicine, Inje University College of Medicine, Busan, Korea3Department of Laboratory Medicine, Gyeongsang National University College of Medicine, Jinju, Korea.4Departments of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea5Department of Laboratory Medicine, Dong-A University College of Medicine, Busan, Korea6Department of Clinical Pathology, School of Medicine, Kyungpook National University, Daegu, Korea *These authors contributed equally to this work. Correspondence to Sunjoo Kim, E-mail: sjkim8239@hanmail.net Ann Clin Microbiol 2025;28(2):10. https://doi.org/10.5145/ACM.2025.28.2.4Received on 30 May 2025, Revised on 12 June 2025, Accepted on 12 June 2025, Published on 27 June 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: Bacterial antimicrobial resistance (AMR) is a major

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Causes and Clinical Relevance of Inconclusive SARS-CoV-2 Real-Time Reverse Transcription-PCR Test Results

Original article Aram Kim, Heerah Lee, Kyu-Hwa Hur, Heungsup Sung, Mi-Na Kim Department of Laboratory Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea Corresponding to Mi-Na Kim, E-mail: mnkim@amc.seoul.kr Ann Clin Microbiol 2020;23(4):191-199. https://doi.org/10.5145/ACM.2020.23.4.4Received on 23 August 2020, Revised on 28 Septenber 2020, Accepted on 13 October 2020, Published on 20 December 2020.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Inconclusive SARS-CoV-2 real-time reverse transcription-PCR (rRT-PCR) test results, which are positive for one or more target genes but not all, are problematic in clinical laboratories. In this study, we aimed to investigate the cause and clinical relevance of such inconclusive results. Methods: rRT-PCR was performed using the Allplex 2019-nCoV assay kit (Seegene Inc., Korea) targeting the following three genes: E, RdRp, and N. For all inconclusive test results reported from March to June 2020, the frequency per kit, lot number, specimen type, cycle threshold (Ct)

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Code Test

Original article Intestinal helminth infections among health examinees: 10-year (2011–2020) nationwide observations in Korea PDF Hyejoo Shin1, Sooji Hong1, Yoon-Hee Lee1, Young-Sung Kim1, Yoon-Joong Joo2, Eun-Hee Lee2, In-One Kim2, Jong-Yil Chai3, Bong-Kwang Jung1 1MediCheck Research Institute, Korea Association of Health Promotion, Seoul,2Korea Association of Health Promotion, Seoul,3Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Seoul, Korea Corresponding to Bong-Kwang Jung, E-mail: mulddang@snu.ac.kr Ann Clin Microbiol 2024;27(2):41-48. https://doi.org/10.5145/ACM.2024.27.2.2Received on 3 April 2024, Revised on 8 May 2024, Accepted on 9 May 2024, Published online 20 June 2024.Copyright © Korean Society of Clinical Microbiology. Abstract Background: A nationwide anti-parasite control program (1969–1995) successfully reduced soil-transmitted helminth infections; however, fish-borne trematode infections persisted in some areas. Since the 2012 National Parasite Infection Survey, information on the current status of intestinal helminth infections has not been updated. Analysis of the current trends in intestinal helminth infections is necessary to prevent and

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Four genotypes of carbapenem-resistant Acinetobacter baumannii strains lacking OXA-23 production in Korea

Brief communication Young Ah Kim1, Seok Hoon Jeong2,3, Jong Hee Shin4, Kyeong Seob Shin5, Jeong Hwan Shin6, Young Ree Kim7, Hyun Soo Kim8, Young Uh9, Nam Hee Ryoo10 1Department of Laboratory Medicine, National Health Insurance Service Ilsan Hospital, Goyang, 2Department of Laboratory Medicine, Yonsei University College of Medicine, Seoul, 3Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, 4Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, 5Department of Laboratory Medicine, Chungbuk National University College of Medicine, Cheongju, 6Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, 7Department of Laboratory Medicine, Jeju National University, College of Medicine, Jeju, 8Department of Laboratory Medicine, Hallym University Dongtan Sacred Heart Hospital, Hallym University College of Medicine, Hwaseong, 9Department of Laboratory Medicine, Yonsei University Wonju College of Medicine, Wonju, 10Department of Laboratory Medicine, Keimyung University School of Medicine, Daegu, Korea Corresponding to Young Ah

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Anisakidosis in humans and animals and detection of anisakid larvae in fish and cephalopods in Korea: a literature review (1971-2022)

Review article Jong-Yil Chai1, Woon-Mok Sohn2, Bong-Kwang Jung3 1Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Seoul2Department of Parasitology and Tropical Medicine, Gyeongsang National University College of Medicine, Jinju;3MediCheck Research Institute, Korea Association of Health Promotion, Seoul, Korea Corresponding to Jong-Yil Chai, E-mail: cjy@snu.ac.kr Ann Clin Microbiol 2024;27(2):93-130. https://doi.org/10.5145/ACM.2024.27.2.6Received on 3 April 2024, Revised on 23 April 2024, Accepted on 29 April 2024, Published on 20 June 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Human anisakiasis (or anisakidosis) is a disease caused by the ingestion of marine fish or cephalopods infected with anisakid nematode larvae of the genera Anisakis, Pseudoterranova, Contracaecum, and Hysterothylacium. Anisakiasis is a clinically important disease that often manifests as an acute abdominal syndrome requiring emergency medical attention and care. In Korea, at

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Intestinal helminth infections among health examinees: 10-year (2011–2020) nationwide observations in Korea

Original article Hyejoo Shin1, Sooji Hong1, Yoon-Hee Lee1, Young-Sung Kim1, Yoon-Joong Joo2, Eun-Hee Lee2, In-One Kim2, Jong-Yil Chai3, Bong-Kwang Jung1 1MediCheck Research Institute, Korea Association of Health Promotion, Seoul,2Korea Association of Health Promotion, Seoul,3Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Seoul, Korea Corresponding to Bong-Kwang Jung, E-mail: mulddang@snu.ac.kr Ann Clin Microbiol 2024;27(2):41-48. https://doi.org/10.5145/ACM.2024.27.2.2Received on 3 April 2024, Revised on 8 May 2024, Accepted on 9 May 2024, Published online 20 June 2024.Copyright © Korean Society of Clinical Microbiology.This is an Open Access article which is freely available under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (https://creativecommons.org/licenses/by-nc-nd/4.0/). Abstract Background: A nationwide anti-parasite control program (1969–1995) successfully reduced soil-transmitted helminth infections; however, fish-borne trematode infections persisted in some areas. Since the 2012 National Parasite Infection Survey, information on the current status of intestinal helminth infections has not been updated. Analysis of the current trends in intestinal

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Two Cases of Chronic Otitis Media caused by Aspergillus terreus

Case report PDF Sung Hee Han, M.D., Mi Ae Lee, M.D. and Wha Soon Chung, M.D. Department of Clinical Pathology, College of Medicine, Ewha Womans University, Seoul, Korea Corresponding to Mi Ae Lee, E-mail: miae@mm.ewha.ac.kr Ann Clin Microbiol 1999;2(2):212-215.Copyright © Korean Society of Clinical Microbiology. Abstract Fungi have been recognized as a significant cause of external otitis and it may be the primary pathogen or be part of a mixed infection. In the immunocompromised host, fungus is capable of producing infection in inner ear or middle ear. Otomycoses are most frequently caused by Aspergillus spp. and Candida spp. There are few reports that Aspergillus species other than A. fumigatus, A. niger and A. flavus have caused chronic otitis media. We report two cases of chronic otitis media caused by Aspergillus terreus in Korea. One case is a 7-year-old girl who had recurrent serous otorrhea and otalgia for 4 years, was reattended otolaryngology clinics with otorrhea of 3 days durations and another is a

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An Outbreak of Astrovirus Infection of Newborns with Hemorrhagic Diarrhea in a Neonatal Unit

Original article PDF Jongyoun Yi1, Jae-Kyoo Lee1, Eun-Hee Chung2, Dong Hee Cho3, and Eui-Chong Kim1 Department of Laboratory Medicine, Seoul National University College of Medicine1, Department of Pediatrics, Dankook University College of Medicine2, Department of Laboratory Medicine, Sungkyunkwan University School of Medicine3, Republic of Korea Corresponding to Eui-Chong Kim, E-mail: euichong@snu.ac.kr Ann Clin Microbiol 2004;7(1):55-58.Copyright © Korean Society of Clinical Microbiology. Abstract Background : We investigated the causative agents of hemorrhagic diarrhea which occurred in newborn babies in a hospital nursery in July, 2002. Rotavirus was not confirmed as the cause because only a few patients were positive for rotavirus test while most others with hemorrhagic diarrhea were negative. Therefore, patients with bloody stool were tested for Salmonella, Shigella, rotavirus, adenovirus, enterovirus, astrovirus, and enterohemorrhagic Escherichia coli (EHEC). Methods : Bloody stools from 12 newborns with hemorrhagic diarrhea were tested. Polymerase chain reaction (PCR) of shiga-toxin gene was performed for EHEC. Rotavirus and adenovirus

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