TT Virus (TTV) Infection in General Population, Chronic Liver Diseases, Hemodialysis, and Transfused Patients
Original article PDF Woon Bo Heo1, Nan Young Lee1, Kyu Young Jeong2, Won Kil Lee1 Department of Clinical Pathology1, School of Medicine, Kyungpook National University, Taegu; and Department of Laboratory Medicine2, Jeju Joongang Hospital, Jeju, Korea Corresponding to Won Kil Lee, E-mail: leewk@kyungpook.ac.kr Ann Clin Microbiol 2006;9(1):7-12.Copyright © Korean Society of Clinical Microbiology. Abstract Background: TT virus (TTV), isolated initially from a Japanese patient with posttransfusion hepatitis of unknown etiology, was suggested to be a new causative agent of hepatitis. However, it has been found to infect both healthy and diseased individuals and numerous studies have raised questions about its pathogenic role in hepatitis. In order to study its prevalence and clinical impact on hepatitis, we assessed the frequency of TTV DNA. Methods: Serum samples were obtained from 60 cases of the controls, 77 cases of chronic liver diseases, 44 cases of hemodialyzed patients, and 65 cases of transfused patients.