Original article PDF Jung Hyun Lee1, Il Kwon Bae2, Su Bong Kwon2, Seok Hoon Jeong2,Gun Jo Woo3, Jongwook Lee4, Wee Gyo Lee5, Jung Oak Kang6, Ji Young Ahn7, Seong Geun Hong8, Jong Hee Shin9, Young Uh10, Yeon Jun Park11, Eui-Chong Kim12, Kyungwon Lee13, Dongeun Yong13 Departments of Pediatrics1 and Laboratory Medicine2, Kosin University College of Medicine; Division of Food Microbiology, Korea Food and Drug Administration3; Departments of Laboratory Medicine, Keonyang University College of Medicine4, Ajou University College of Medicine5, Hanyang University College of Medicine6, Sooncheonhyang University College of Medicine7, Pochon CHA University College of Medicine8, Chonnam National University Medical school9 , Yonsei University Wonju College of Medicine10, The Catholic University of Korea College of Medicine11, Seoul National University College of Medicine12, Yonsei University College of Medicine13 Corresponding to Seok Hoon Jeong, E-mail: kscpjsh@ns.kosinmed.or.kr Ann Clin Microbiol 2004;7(2):111-118.Copyright © Korean Society of Clinical Microbiology. Abstract Background : The aims of this study were

Original article PDF In-Suk Kim, M.D., Chang-Seok Ki, M.D., Eun-Hae Cho, M.D., Kwang Woong Lee, M.D.1, Sung-Ju Kim, M.D.1, Jae-Won Joh, M.D.1, Beom Kim, M.D.2, Woo seong Huh, M.D.2, Ha Young Oh, M.D.2, Nam-Yong Lee, M.D., Sun Hee Kim, M.D., and Jong-Won Kim, M.D. Department of Laboratory Medicine, Surgery1, and Internal Medicine2, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Korea Corresponding to Jong-Won Kim, E-mail: jwonk@smc.samsung.co.kr Ann Clin Microbiol 2004;7(1):59-65.Copyright © Korean Society of Clinical Microbiology. Abstract Background : Human parvovirus B19 infection has been known to cause chronic anemia, pure red cell aplasia, glomerulopathy and allograft dysfunction in kidney transplant (KT) recipients. The aim of this study was to evaluate the prevalence and clinical significance of B19 infection in KT recipients. Methods : Five hundred and thirty seven serum samples from 167 KT recipients were included in the present study. The prevalence of B19 infection was based

Case report PDF Bong Joon Oh, Jong Hee Shin, Kwang Jin Kim, Duck Cho, Seong Jung Kee, Myung Gun Shin, Soon Pal Suh, and Dong Wook Ryang Department of Laboratory Medicine, Chonnam National University Medical School, Gwangju, Korea Corresponding to Jong Hee Shin, E-mail: shinjh@chonnam.ac.kr Ann Clin Microbiol 2005;8(2):189-193.Copyright © Korean Society of Clinical Microbiology. Abstract Fusarium species are representative of the emerging group of filamentous molds, which cause respiratory and disseminated infections in immunocompromised patients. To date, only five cases of respiratory or disseminated skin infections due to Fusarium spp. have been described in Korea. Here we describe a fungemia case of Fusarium oxysporum in a 3-year old boy who was neutropenic following chemotheray for leukemia. Fever, painful macules on both extremities and phlebitis on the site of venous blood sampling developed on the day 35 of admission. All four blood cultures obtained on hospital days 37, 38, 40 and 42 yielded the same F.

Original article PDF Ji Hae Kang1, Il Kwon Bae2, Su Bong Kwon2, Seok Hoon Jeong2*, Jongwook Lee3, Wee Gyo Lee4, Jung Oak Kang5, Ji Young Ahn6, Seong Geun Hong7, Jong Hee Shin8, Young Uh9, Yeon Jun Park10, Eui-Chong Kim11, Kyungwon Lee12, Dongeun Yong12, and Gun Jo Woo13 Departments of Pediatrics1and Laboratory Medicine2, Kosin University College of Medicine, Busan; Department of Laboratory Medicine3, Keonyang University College of Medicine, Daejeon; Department of Laboratory Medicine4, Ajou University College of Medicine, Suwon; Department of Laboratory Medicine5, Hanyang University College of Medicine, Guri; Department of Laboratory Medicine6, Sooncheonhyang University College of Medicine, Gumi; Department of Laboratory Medicine7, Pochon Cha University College of Medicine, Sungnam; Department of Laboratory Medicine8, Chonnam National University Medical School, Gwangju; Department of Laboratory Medicine9, Yonsei University Wonju College of Medicine, Wonju; Department of Laboratory Medicine10, The Catholic University of Korea College of Medicine, Seoul; Department of Laboratory Medicine11, Seoul National University

Original article PDF Il Kwon Bae1, Yu Nae Lee1, Seok Hoon Jeong1, Kyungwon Lee2, Dongeun Yong2, Jongwook Lee3, Seong Geun Hong4, Eui-Chong Kim5, Yeon Jun Park6, Tae Yeal Choi7, Young Uh8, Jong Hee Shin9, Wee Gyo Lee10, Ji young Ahn11, Sung-Hee Lee12, Gun-Jo Woo13, Hyo-Sun Kwak13 Department of Laboratory Medicine1, Kosin University College of Medicine, Busan; Department of Laboratory Medicine2, Yonsei University College of Medicine, Seoul; Department of Laboratory Medicine3, Keonyang University College of Medicine, Daejeon; Department of Laboratory Medicine4, Pochon Cha University College of Medicine, Sungnam; Department of Laboratory Medicine5, Seoul National University College of Medicine; Department of Laboratory Medicine6, The Catholic University College of Medicine; Department of Laboratory Medicine7, Hanyang University College of Medicine, Seoul; Department of Laboratory Medicine8, Yonsei University Wonju College of Medicine9, Wonju; Department of Laboratory , Chonnam National University College of Medicine, Gwangju; Department of Laboratory Medicine10, Ajou University College of Medicine, Suwon; Department

Original article PDF Geon Park, M.D.1, Sook-Jin Jang, M.D.1,2, Ho-Jong Jeon, M.D.3, Seong-Hwan Kim, M.D.4, Mi-Ja Lee, M.D.3, Jin-Hee Kim, M.S.1, Sung-Heui Shin, M.D.2, Bidur Prasad Chaulagain, M.S.1,2, Dong-Min Kim, M.D.5, Dae-Soo Moon, M.D.1, Young-Jin Park, M.D.1 Department of Laboratory Medicine and Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea Corresponding to Sook Jin Jang, E-mail: sjbjang@chosun.ac.kr Ann Clin Microbiol 2007;10(2):84-89.Copyright © Korean Society of Clinical Microbiology. Abstract Background: In hepatocellular carcinoma (HCC), the frequency of p53 mutation and the association with hepatitis B virus (HBV) infection varies with geographic locations and risk factors. The aim of this study was to determine the frequency of codon 249 mutation of p53, p53 overexpression, and HBV DNA positivity and to observe the relationship between them in Korean HCC. Methods: We analyzed overexpression of p53 in hepatoma tissue from 17 HCC patients by immunohistochemistry (IHC), specific mutations at the third base position of

Original article PDF Jeong Man Kim1, Kyeong Hee Kim1, Sun Min Lee2, Kwang Won Seo3, Joseph Jeong4, Sung-Ryul Kim4, Seon Ho Lee4, Eun Yup Lee2, Chulhun L. Chang2,5 1Department of Laboratory Medicine, Dong-A University College of Medicine, 2Department of Laboratory Medicine, Pusan National University School of Medicine, Busan; Departments of 3Internal Medicine and 4Laboratory Medicine, Ulsan University College of Medicine, Ulsan; 5Korean Institute of Tuberculosis, The Korean National Tuberculosis Association, Seoul, Korea Corresponding to Chulhun L. Chang, E-mail: cchl@pusan.ac.kr Ann Clin Microbiol 2007;10(2):143-149.Copyright © Korean Society of Clinical Microbiology. Abstract Background: It is recommended that all rapidly growing mycobacteria (RGM) isolated from patients with mycobacteriosis are subjected to antimicrobial susceptibility testing. The current study was aimed to perform susceptibility test on clinical strains of RGM isolated from patients with mycobacteriosis and to determine the clinical significance of the isolates. Methods: For 17 patients with RGM infection from 2002 to 2006 at Ulsan University

Original article PDF Hyukmin Lee1, Chang Ki Kim2, Jongwook Lee3, Sung-Hee Lee4, Ji Young Ahn5, Seong Geun Hong6, Yeon Jun Park7, Seok Hoon Jeong8, Eui-Chong Kim9, Wee Kyo Lee10, Young Uh11, Jong Hee Shin12, Tae Yeal Choi13, Hyo-Sun Kwak14, Kyungwon Lee2 Department of Laboratory Medicine, 1Kwandong University College of Medicine, Goyang; 2Yonsei University College of Medicine, Seoul; 3Keonyang University Medical College, Daejeon; 4Cheju Hanmaeum Hospital, Jeju; 5Sooncheonhyang University College of Medicine, Gumi; 6Pochon CHA University College of Medicine, Seongnam; 7 The Catholic University of Korea College of Medicine, Seoul; 8Kosin University College of Medicine, Busan; 9Seoul National University College of Medicine, Seoul; 10Ajou University College of Medicine, Suwon; 11Yonsei University Wonju College of Medicine, Wonju; 12Chonnam National Univeristy Medical School, Gwangju; 13Hanyang University College of Medicine, Seoul; 14Food Microbiology Division, Center for Food Safety Evaluation, Korea Food and Drug Administration, Seoul, Korea Corresponding to Kyungwon Lee, E-mail: leekcp@yumc.yonsei.ac.kr Ann Clin Microbiol 2007;10(1):59-69.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Emergence and spread of antimicrobial

Original article PDF Sun Yang Chung1, Ji Youn Sung2, Kye Chul Kwon2, Jong Woo Park2, Chi Seon Ko2, So Youn Shin2, Jeong Hoon Song2, Sun Hoe Koo2 1Health Promotion Center, Samsung Medical Center, Seoul, 2Department of Laboratory Medicine, Chungnam National University College of Medicine, Daejeon, Korea Corresponding to Sun Hoe Koo, E-mail: shkoo@cnu.ac.kr Ann Clin Microbiol 2008;11(2):98-106.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Recently, there have been reports of infections with multidrug-resistant Pseudomonas aeruginosa. To determine the mechanism of the resistance, we investigated the prevalence of Ambler class A and D β-lactamases, their extended-spectrum derivatives, and class B and D carbapenemase in multidrug-resistant P. aeruginosa isolates. Methods: During the period of March 2006 to May 2007, clinical isolates of multidrug-resistant P. aeruginosa were collected from patients in Chungnam National University Hospital, Daejeon, Korea. Inhibitor-potentiated disk diffusion tests were used for the screening of metallo-β-lactamase (MBL) production. PCR and DNA sequencing were conducted for the detection of β-lactamase genes. We also employed the

Original article PDF Joseph Jeong, Sung-Ryul Kim, Chulhun L. Chang1, Seon Ho Lee Department of Laboratory Medicine, Ulsan University Hospital, Ulsan; 1Department of Laboratory Medicine, College of Medicine, Pusan National University, Busan, Korea Corresponding to Seon Ho Lee, E-mail: 690519@hitel.net Ann Clin Microbiol 2008;11(1):34-42.Copyright © Korean Society of Clinical Microbiology. Abstract Background: Infections caused by nontuberculous mycobacteria (NTM) are significantly increasing over the last decade. Due to the uncertainty in the clinical significance of these organisms, their effective diagnosis and treatment has been challenging. The purpose of this study was to investigate the distribution and clinical significance of NTM in clinical specimens. Methods: Acid-fast culture positive 3,107 clinical specimens were identified by mycolic acid analysis using high performance liquid chromatography (HPLC.) The HPLC patterns of 384 NTM strains were compared with those of standard mycobacterium species. Clinical significance of NTM was investigated by a retrospective study including acid-fast stain and culture, medical history,