A Case Report of Saccharomyces cerevisiae Fungemia in a Premature Infant Following Probiotic Treatment

Jaewoong  Lee1   Hyunjung Kim1   Hae Kyung  Lee1*   Yeon-Joon  Park2   

1 Department of Laboratory Medicine, Uijeongbu St. Mary’s Hospital, Uijeongbu
2 Department of Laboratory Medicine, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul

* Corresponding author:Tel: +82-31-820-3159 ,Fax: +82-31-847-6266 E-mail: hkl@catholic.ac.kr


Probiotics are used to restore and maintain the healthy intestinal microflora. Although Saccharomyces cerevisiae (SC) is considered as a non-pathogenic yeast, administration of SC as a probiotic is associated with a rare cause of fungemia in immunocompromised patients with central venous catheter insertion. We encountered a case of SC fungemia in a premature infant who presented with respiratory distress syndrome and had undergone central venous catheterization.

Figures & Tables

Fig. 1. Microscopic image (A) and colony morphology (B) of Saccharomyces cerevisiae from the patient’s blood specimen.