Ann Clin Microbiol 2022;25:137-145. Antimicrobial resistance patterns of Acinetobacter baumannii and Pseudomonas aeruginosa isolated from vulnerable patients in Korea, 2021
| ANTI | CA (n = 31) | HA (n = 198) | P-value | Non-ICU (n = 97) | ICU (n = 132) | P-value | Inpatient (n = 206) | Outpatient (n = 23) | P-value | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | No. | (%) | |||||||
| PIP | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 13 | (41.94) | 15 | (7.58) | 24 | (24.74) | 4 | (3.03) | 18 | (8.74) | 10 | (43.48) | ||||||
| R | 18 | (58.06) | 183 | (92.42) | 73 | (75.26) | 128 | (96.97) | 188 | (91.26) | 13 | (56.52) | ||||||
| SAM | 0.0932 | 0.0009 | 0.0007 | |||||||||||||||
| S or I | 17 | (54.84) | 77 | (38.89) | 52 | (53.61) | 42 | (31.82) | 77 | (37.38) | 17 | (73.91) | ||||||
| R | 14 | (45.16) | 121 | (61.11) | 45 | (46.39) | 90 | (68.18) | 129 | (62.62) | 6 | (26.09) | ||||||
| TZP | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 13 | (41.94) | 15 | (7.58) | 24 | (24.74) | 4 | (3.03) | 18 | (8.74) | 10 | (43.48) | ||||||
| R | 18 | (58.06) | 183 | (92.42) | 73 | (75.26) | 128 | (96.97) | 188 | (91.26) | 13 | (56.52) | ||||||
| CAZ | < 0.0001 | < 0.0001 | 0.0002 | |||||||||||||||
| S or I | 13 | (41.94) | 18 | (9.09) | 27 | (27.84) | 4 | (3.03) | 21 | (10.19) | 10 | (43.48) | ||||||
| R | 18 | (58.06) | 180 | (90.91) | 70 | (72.16) | 128 | (96.97) | 185 | (89.81) | 13 | (56.52) | ||||||
| FEP | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 13 | (41.94) | 20 | (10.10) | 26 | (26.80) | 7 | (5.3) | 22 | (10.68) | 11 | (47.83) | ||||||
| R | 18 | (58.06) | 178 | (89.90) | 71 | (73.20) | 125 | (94.7) | 184 | (89.32) | 12 | (52.17) | ||||||
| IPM | < 0.0001 | < 0.0001 | 0.0004 | |||||||||||||||
| S or I | 12 | (38.71) | 16 | (8.08) | 24 | (24.74) | 4 | (3.03) | 19 | (9.22) | 9 | (39.13) | ||||||
| R | 19 | (61.29) | 182 | (91.92) | 73 | (75.26) | 128 | (96.97) | 187 | (90.78) | 14 | (60.87) | ||||||
| MEM | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 13 | (41.94) | 16 | (8.08) | 25 | (25.77) | 4 | (3.03) | 19 | (9.22) | 10 | (43.48) | ||||||
| R | 18 | (58.06) | 182 | (91.92) | 72 | (74.23) | 128 | (96.97) | 187 | (90.78) | 13 | (56.52) | ||||||
| AMK | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 17 | (54.84) | 33 | (16.67) | 39 | (40.21) | 11 | (8.33) | 36 | (17.48) | 14 | (60.87) | ||||||
| R | 14 | (45.16) | 165 | (83.33) | 58 | (59.79) | 121 | (91.67) | 170 | (82.52) | 9 | (39.13) | ||||||
| GEN | < 0.0001 | < 0.0001 | 0.0004 | |||||||||||||||
| S or I | 15 | (48.39) | 25 | (12.63) | 33 | (34.02) | 7 | (5.3) | 29 | (14.08) | 11 | (47.83) | ||||||
| R | 16 | (51.61) | 173 | (87.37) | 64 | (65.98) | 125 | (94.7) | 177 | (85.92) | 12 | (52.17) | ||||||
| TOB | < 0.0001 | < 0.0001 | < 0.0001 | |||||||||||||||
| S or I | 16 | (51.61) | 32 | (16.16) | 39 | (40.21) | 9 | (6.82) | 35 | (16.99) | 13 | (56.52) | ||||||
| R | 15 | (48.39) | 166 | (83.84) | 58 | (59.79) | 123 | (93.18) | 171 | (83.01) | 10 | (43.48) | ||||||
| CIP | < 0.0001 | < 0.0001 | 0.0002 | |||||||||||||||
| S or I | 12 | (38.71) | 14 | (7.07) | 22 | (22.68) | 4 | (3.03) | 17 | (8.25) | 9 | (39.13) | ||||||
| R | 19 | (61.29) | 184 | (92.93) | 75 | (77.32) | 128 | (96.97) | 189 | (91.75) | 14 | (60.87) | ||||||
| MIN | > 0.9999 | > 0.9999 | > 0.9999 | |||||||||||||||
| S or I | 31 | (100.00) | 196 | (98.99) | 96 | (98.97) | 131 | (99.24) | 204 | (99.03) | 23 | (100.00) | ||||||
| R | – | 0 | 2 | (1.01) | 1 | (1.03) | 1 | (0.76) | 2 | (0.97) | – | 0 | ||||||
| TGC | 0.5474 | 0.3123 | 0.3264 | |||||||||||||||
| S or I | 29 | (93.55) | 173 | (87.37) | 88 | (90.72) | 114 | (86.36) | 183 | (88.83) | 19 | (82.61) | ||||||
| R | 2 | (6.45) | 25 | (12.63) | 9 | (9.28) | 18 | (13.64) | 23 | (11.17) | 4 | (17.39) | ||||||
| CST | > 0.9999 | > 0.9999 | > 0.9999 | |||||||||||||||
| S or I | 31 | (100.00) | 196 | (98.99) | 96 | (98.97) | 131 | (99.24) | 204 | (99.03) | 23 | (100.00) | ||||||
| R | – | 0 | 2 | (1.01) | 1 | (1.03) | 1 | (0.76) | 2 | (0.97) | – | 0 | ||||||
Bold form: statistically significant. Abbreviations: ANTI, antimicrobials; CA, community-acquired infection; HA, healthcare-associated infection; ICU, intensive care unit; PIP, piperacillin; SAM, ampicillin-sulbactam; TZP, piperacillin-tazobactam; CAZ, ceftazidime; FEP, cefepime; IPM, imipenem; MEM, meropenem; AMK, amikacin; GEN, gentamicin; TOB, tobramycin; CIP, ciprofloxacin; MIN, minocycline; TGC, tigecycline; CST, colistin; S, susceptible; I, intermediate; R, resistant.