Table 2. New breakpoints of aminopenicillins for Enterobacterales according to infection types and formulations in EUCAST version 13

Ann Clin Microbiol 2023;26:51-57. Introduction to the revised international guidelines on breakpoints for antimicrobial susceptibility testing

Table 2. New breakpoints of aminopenicillins for Enterobacterales according to infection types and formulations in EUCAST version 13

Aminopenicillins	Formulations/Infection types	Disk diffusion (mm)			MIC (µg/mL)
Aminopenicillins	Formulations/Infection types	S	I	R	S	I	R
Ampicillin	IV	≥14	–	≤13	≤8	–	≥16
Ampicillin	Oral/uUTI only
Ampicillin-sulbactam	IV	≥14	–	≤13	≤8	–	≥16
Ampicillin-sulbactam	Oral/uUTI only
Amoxicillin	IV				≤8	–	≥16
	Oral/cUTI				–	≤8	≥16
	Oral/uUTI only				≤8	–	≥16
	Oral/other indications				≤8	–	≥16
Amoxicillin-clavulanic acid	IV	≥19	–	≤18	≤8	–	≥16
	Oral/cUTI	≥19	–	≤18	–	≤8	≥16
	Oral/uUTI only	≥17	–	≤16	≤32	–	≥64
	Oral/other indications	≥17	–	≤16	≤8	–	≥16

Abbreviations: EUCAST, the European Committee on Antimicrobial Susceptibility Testing; MIC, minimum inhibitory concentration; S, susceptible; I, intermediate; R, resistant; IV, intravenous; uUTI, uncomplicated urinary tract infection; cUTI, complicated urinary tract infection.