Ann Clin Microbiol 2023;26:103-115. Clinical usefulness of procalcitonin/albumin and blood urea nitrogen/albumin ratios for the early detection of bacteremia

Table 2. Logistic regression analysis for relation between bacteremia and biochemical variables
VariableGram negative bacteremia (n = 77)
UnivariableMultivariable
OR (95% CI)P-valueOR (95% CI)*P-valueOR (95% CI)†P-value
Procalcitonin1.03 (1.02 – 1.04)< 0.0011.02 (1.02 – 1.03)< 0.0011.02 (1.02 – 1.03)< 0.001
hsCRP1.05 (1.03 – 1.07)< 0.0011.03 (1.01 – 1.05)0.0201.03 (1.01 – 1.06)0.010
Lactic acid1.07 (1.01 – 1.13)0.0201.04 (0.97 – 1.12)0.2841.03 (0.96 – 1.11)0.424
BUN1.01 (1.01 – 1.02)< 0.0011.00 (0.99 – 1.01)0.6881.00 (0.99 – 1.01)0.893
Albumin0.37 (0.25 – 0.54)< 0.0010.51 (0.37 – 0.80)0.0030.55 (0.35 – 0.87)0.010
VariableGram positive bacteremia (n = 55)
UnivariableMultivariable
OR (95% CI)P-valueOR (95% CI)*P-valueOR (95% CI)†P-value
Procalcitonin1.01 (1.00 – 1.02)0.1441.00 (0.99 – 1.01)0.8331.00 (0.99 – 1.01)0.940
hsCRP1.02 (1.00 – 1.04)0.2871.00 (0.97 – 1.03)0.8650.99 (0.97 – 1.03)0.875
Lactic acid1.10 (1.04 – 1.17)0.0011.08 (1.02 – 1.15)0.0111.08 (1.02 – 1.15)0.010
BUN1.02 (1.01 – 1.03)< 0.0011.02 (1.01 – 1.02)0.0031.02 (1.00 – 1.03)0.010
Albumin0.41 (0.26 – 0.62)< 0.0010.49 (0.31 – 0.77)0.0020.50 (0.31 – 0.81)0.005

*Model 1: adjusted for age, sex; †Model 2: adjusted for age, sex, white blood cell count, platelet count, creatinine, total bilirubin, glucose. Abbreviations: OR, odds ratio; CI, confidence interval; hsCRP, high sensitivity C-reactive protein; BUN, blood urea nitrogen.