Table 2. Species distribution of Candida isolates from sterile and nonsterile clinical specimens

Ann Clin Microbiol 2024;27(3):185-196. Seasonality and epidemiological trends in species distribution and antifungal susceptibility of Candida species isolated from various clinical specimens conducted during 2011–2022, Korea: a retrospective surveillance study

Table 2. Species distribution of Candida isolates from sterile and nonsterile clinical specimens

Species	Respiratory	Pus/Wound			Urine	Stool	Tissue	Vaginal discharge	Cath tip	Non-sterile Total	Blood	Ascitic fluid	Pleural fluid	Other sterile fluid^b	Sterile Total	Sterile vs. Non-sterile p-value
Species	Respiratory	Ear discharge	Eye discharge	Other pus/wound	Urine	Stool	Tissue	Vaginal discharge	Cath tip	Non-sterile Total	Blood	Ascitic fluid	Pleural fluid	Other sterile fluid^b	Sterile Total	Sterile vs. Non-sterile p-value
C. albicans	194	10	3	87	2,967	1		165	56	3,483	461	19	15	178	673	0.2725
C. tropicalis	117	4		36	1,632			9	25	1,823	154	8	12	56	230	< 0.0001^a
C. glabrata	4	1		13	1,131		2	23	13	1,187	206	12	6	16	240	0.2272
C. parapsilosis	2	108	4	19	271		1		14	419	123		1	7	131	< 0.0001^a
C. utilis		1		1	85			1		88	4				4	0.0026^a
C. famata	3	7			135			2		147	9	1	1		11	0.0021^a
C. krusei	11			2	31			3		47	4	1	12	5	22	0.0001^a
C. lusitaniae	6				44				1	51	8			4	12	0.4218
C. haemulonii		31	1						3	35	0				0	–
C. orthopsilosis		3			9				1	13	11				11	0.0002^a
C. guilliermondii		2			11				1	14	15	1			16	< 0.0001^a
C. kefyr										0	1				1	–
C. auris		8							1	9	0				0	–
C. ciferrii		3			1					4	0				0	–
C. norvegensis					2					2	0				0	–
C. lipolytica					1					1	0				0	–
C. inconspicua	1									1	0				0	–
Total	338	178	8	158	6,320	1	3	203	115	7,324	996	42	47	266	1,351

^ap ＜ 0.05.
^bOther sterile fluids included bile, amniotic fluid, intraocular (vitreous and aqueous) fluid, homovac drainage, and percutaneous transhepatic biliary drainage.
Overall, C. albicans was the most commonly identified species in almost all samples, except pus. The most common non-albicans Candida species isolated from respiratory specimens was C. tropicalis whereas those isolated from urine and pus specimens were C. tropicalis and C. parapsilosis, respectively. In vaginal discharge, C. albicans was the most common species identified, followed by C. glabrata. Candida was the most common species with 996 strains isolated from blood, (73.7%), pleural fluid (3.5%), and ascitic fluid (3.1%).