Ann Clin Microbiol 2024;27(3):185-196. Seasonality and epidemiological trends in species distribution and antifungal susceptibility of Candida species isolated from various clinical specimens conducted during 2011–2022, Korea: a retrospective surveillance study
| Candida infection | 2012 | 2013 | 2014 | 2015 | 2016 | 2017 | 2018 | 2019 | 2020 | 2021 | 2022 | 2012-2022 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Candida spp. | 465 | 401 | 414 | 615 | 794 | 550 | 802 | 954 | 1,282 | 1,092 | 1,164 | 8,533 |
| (0.84) | (0.66) | (0.67) | (0.95) | (1.20) | (0.94) | (1.13) | (1.36) | (2.15) | (1.71) | (1.77) | (1.22) | |
| Candida albicans | 216 | 216 | 207 | 267 | 403 | 243 | 387 | 519 | 577 | 503 | 540 | 4,078 |
| (46.45) | (53.87) | (50.00) | (43.41) | (50.76) | (44.18) | (48.25) | (54.40) | (45.01) | (46.06) | (46.39) | (47.79) | |
| NAC | 249 | 185 | 207 | 348 | 391 | 307 | 415 | 435 | 705 | 589 | 624 | 4,455 |
| (53.55) | (46.13) | (50.00) | (56.59) | (49.24) | (55.82) | (51.75) | (45.60) | (54.99) | (53.94) | (53.61) | (52.21) | |
| C. tropicalis | 41 | 61 | 94 | 139 | 198 | 191 | 244 | 207 | 294 | 251 | 248 | 1,968 |
| (8.82) | (15.21) | (22.71) | (22.60) | (24.94) | (34.73) | (30.42) | (21.70) | (22.93) | (22.99) | (21.31) | (23.06) | |
| C. glabrata | 94 | 34 | 34 | 135 | 118 | 66 | 73 | 143 | 272 | 210 | 226 | 1,405 |
| (20.22) | (8.48) | (8.21) | (21.95) | (14.86) | (12.00) | (9.10) | (14.99) | (21.22) | (19.23) | (19.42) | (16.47) | |
| C. parapsilosis | 23 | 23 | 21 | 44 | 38 | 17 | 69 | 45 | 88 | 74 | 99 | 541 |
| (4.95) | (5.74) | (5.07) | (7.15) | (4.79) | (3.09) | (8.60) | (4.72) | (6.86) | (6.78) | (8.51) | (6.34) | |
| Total | 55,448 | 60,344 | 61,735 | 64,943 | 66,428 | 58,371 | 71,027 | 69,998 | 59,669 | 63,762 | 65,685 | 697,410 |
Values are presented as n (%) or n.
In 2019, of the 954 positive cases for Candida, C. albicans and NAC accounted for 54.4 % (519 cases) and 45.6 % (435 cases) , respectively. C. albicans was identified significantly more frequently (p < 0.05). In 2020, this trend was reversed and significantly more NACs were identified. This trend is expected to continue after the year 2020.
Abbreviation: NAC, non-albicans Candida.