Fig. 2. Application of diagnostic stewardship to blood culture practice in a clinical microbiology laboratory. After BACTEC loading at 1-17 13:07, there were six moments of reports including a critical value report (CVR) and an infection control alert until the final report: (1) Positive signal at 1-18 01:28, (12.4 h from an aerobic bottle); (2) Gram stain results as gram-negative rods seen at 1-18 02:24; (3) Call to clinician at 1-18 02:27 recorded as a CVR, which initiates an automatic consult with infectious disease specialists for antimicrobial stewardship program, 3. KPC/ CTX-M producing Klebsiella pneumoniae positive by BCID2 at 1-18 03:49; (4) Species identification and antimicrobial susceptibility test using colony at 1-19 11:59; (5) Phenotyping and genotyping of carbapenemase at 1-20 10:39; (6) A panic value for issuing an infection control alert.