Ann Clin Microbiol 2025;29(3):10. Macrolide-resistant Mycoplasma pneumoniae: laboratory diagnosis and epidemiology

Table 1. Trend of macrolide-resistant Mycoplasma pneumoniae prevalence and dominant sequence types in Korea
PeriodSample (n)MRMP prevalence (%)Dominant ST / cloneNotesReference
2000–2011
(longitudinal)
2,089 specimens / 255 MP+ / 80 with mutation2.9 (2003) → 62.9 (2011)Not typedNational longitudinal trend[10]
2010
(Oct–Nov)
195 / 17 MP+17.6 (3/17, A2063G)Not typedMP positive in primary clinic (12.1%) vs. tertiary hospital (2.8%)[27]
201594 patients87.2 (82/94)Not typedPediatric; A2063G dominant[33]
2018–20201,063 enrolled / 454 MP+78.4 (all A2063G)Not typedProspective multicenter[34]
2019–20201,228 specimens / 93 MP+Overall 78.5 (73/93); ST3 98.5%; ST14 38.9%ST3 71.0% / ST14 19.4% (3 novel STs)4 hospitals; ST3 → ST14 transition[45]
2023
(Sep–Dec)
474 screened / 374 confirmed87.0Not typed13 major hospitals; corticosteroid co-prescription 55.6%[28]

Not typed indicates that sequence typing was not performed in the original study. Abbreviations: MP, Mycoplasma pneumoniae; MRMP, macrolide-resistant Mycoplasma pneumoniae; ST, sequence type.