Ann Clin Microbiol 2025;29(3):10. Macrolide-resistant Mycoplasma pneumoniae: laboratory diagnosis and epidemiology
| Period | Sample (n) | MRMP prevalence (%) | Dominant ST / clone | Notes | Reference |
|---|---|---|---|---|---|
| 2000–2011 (longitudinal) | 2,089 specimens / 255 MP+ / 80 with mutation | 2.9 (2003) → 62.9 (2011) | Not typed | National longitudinal trend | [10] |
| 2010 (Oct–Nov) | 195 / 17 MP+ | 17.6 (3/17, A2063G) | Not typed | MP positive in primary clinic (12.1%) vs. tertiary hospital (2.8%) | [27] |
| 2015 | 94 patients | 87.2 (82/94) | Not typed | Pediatric; A2063G dominant | [33] |
| 2018–2020 | 1,063 enrolled / 454 MP+ | 78.4 (all A2063G) | Not typed | Prospective multicenter | [34] |
| 2019–2020 | 1,228 specimens / 93 MP+ | Overall 78.5 (73/93); ST3 98.5%; ST14 38.9% | ST3 71.0% / ST14 19.4% (3 novel STs) | 4 hospitals; ST3 → ST14 transition | [45] |
| 2023 (Sep–Dec) | 474 screened / 374 confirmed | 87.0 | Not typed | 13 major hospitals; corticosteroid co-prescription 55.6% | [28] |
Not typed indicates that sequence typing was not performed in the original study. Abbreviations: MP, Mycoplasma pneumoniae; MRMP, macrolide-resistant Mycoplasma pneumoniae; ST, sequence type.