1Department of Laboratory Medicine, Seoul St. Mary Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea
*Corresponding author: E-mail: yiy00@naver.com
The Annals of Clinical Microbiology 2023 26(1):1-9
Received Date: 09 January 2023
Revised Date: 27 February 2023
Accepted Date: 27 February 2023
DOI: 10.5145/ACM.2023.26.1.1
Citation
ABSTRACT
Sexually transmitted infections (STIs) are a major global public health problem, with significant social burden worldwide. Accurate and appropriate diagnosis and treatment of STIs are important for preventing the transmission of STIs as well as major health consequences of untreated STIs, such as infertility and certain cancer. For diagnosis of STIs, the application of conventional culture and immunoassays is limited by their low sensitivity and long turnaround time. Nucleic acid amplification tests for STIs allow for syndromic tests for multiple pathogens simultaneously and show high sensitivity with a short turnaround time. In this review, we discuss the characteristics of commercially available multiplex molecular platforms and the features needed in next-generation syndromic tests for STIs.
