Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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pISSN 2288-0585 eISSN 2288-6850

The Serogroup and Antimicrobial Resistance of Salmonella spp. Isolated from the Clinical Specimens During 6 years in a Tertiary University Hospital

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2004 June Volume 7, Issue 1, pages 72-76.


https://doi.org/10.5145/ACM.2004.07.1.72

The Serogroup and Antimicrobial Resistance of Salmonella spp. Isolated from the Clinical Specimens During 6 years in a Tertiary University Hospital

Soyeon Seo, M.D., and Mi-Ae Lee, M.D.

Department of Laboratory Medicine, College of Medicine, Ewha Womans University Mokdong Hospital, Seoul, Korea

Abstract

Background : Recently, non-typhoidal salmonellosis is increasing and it constituted over 90% of total salmonellosis in 1990s. The antimicrobial resistance of non-typhoidal Salmonella gets higher. So we described the change of serogroup and antimicrobial resistance of Salmonella isolated from clinical specimens in Ewha Womans University Mokdong Hospital during 6 years.

Methods : Clinical specimens were submitted from 1997 to 2002. Stool cultures were inoculated onto MacConkey (MAC) agar and Salmonella-Shigella(SS) agar and into Selenite F (SF) enrichment broth. Identification of Salmonella were performed by Vitek GNI card (BioMerieux, Marcy-I’Eltoile, France) and serotyping were done. Antimicrobial resistance test were performed by Vitek GNS card (BioMerieux, Marcy-I’Eltoile, France).

Results : From 1997 to 2002, 594 strains of Salmonella were isolated. Non-typhoidal Salmonella and Salmonella typhi constituted 94.4% and 5.6%. Non-typhoidal Salmonella were mainly composed of group B (21.5%) and group D (48.0%), but in 2002, group C (12.4%) and group E (27.9%) were increased in number. The antimicrobial resistance rate of non-typhpoidal Salmonella were 28% to ampicillin, 4.1% to SXT, 0.2% to ciprofloxacin and 0.7% to ceftriaxone. The animicrobial resistance rate of group B and D Salmonella showed 37.5% and 32.6% to ampicillin, 7.8% and 4.2% to SXT, respectively.

Conclusions : Serogroup B and D Salmonella were most frequently isolated, but group C and E Salmonella have been increased in 2002. Antimicrobial resistance of group B and D Salmonella were higher than other serogroups and have been increased year by year. (Korean J Clin Microbiol 2004;7(1):72-76)

Keywords

Non-typhoidal Salmonellosis, Serogroup, Antimicrobial resistance, Salmonella typhi