Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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pISSN 2288-0585 eISSN 2288-6850

Patterns of Antimicrobial Susceptibility of the Causative Bacteria of Urinary Tract Infections in Recent Years in an Island Region

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2007 April Volume 10, Issue 1, pages 19-24.


https://doi.org/10.5145/ACM.2007.10.1.19

Patterns of Antimicrobial Susceptibility of the Causative Bacteria of Urinary Tract Infections in Recent Years in an Island Region

Young Ree Kim1, Jung-Sik Huh2, Sung-Ha Kang1
Departments of 1Laboratory Medicine and 2Urology, Cheju National University College of Medicine, Jeju, Korea

Abstract

Background: In order to provide a guideline for empirical treatment of urinary tract infections, we studied a change in causative organisms and antimicrobial susceptibility in our region of an island.

Methods: We reviewed the results of antimicrobial susceptibility and the hospital charts of 3,064 patients with a significant bacteriuria (more than 105 colony forming unit/mL in urine cultures); the patients had been admitted to or seen at the out-patient clinic of Cheju University Hospital during the period from January 2002 to December 2005.

Results: The most common pathogens were Escherichia coli (44.9%), Klebsiella spp. (8.1%), and Pseudomonas spp. (7.0%). In E. coli, the mean percent resistance to ampicillin, trimethoprim-sulfamethoxazole, and ciprofloxacin during the 4-year period was 69.0%, 32.5%, and 24.7%, respectively.

Conclusion: An increasing resistance of common urinary pathogens to known empirical agents such as ampicillin, trimethoprim-sulfamethoxazole, and ciprofloxacin caused a need for a more updated guideline in our region of an island. (Korean J Clin Microbiol 2007;10:19-24)

Keywords

Urinary tract infections, Antimicrobial susceptibility