Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Indexed in KCI, KoreaMed, Synapse, DOAJ
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pISSN 2288-0585 eISSN 2288-6850

Evaluation of SD Bioline Strep A for Rapid Antigen Testing in Elementary Schoolchildren

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2007 April Volume 10, Issue 1, pages 54-58.


https://doi.org/10.5145/ACM.2007.10.1.54

Evaluation of SD Bioline Strep A for Rapid Antigen Testing in Elementary Schoolchildren

Eun-Ha Koh, Sunjoo Kim

Department of Laboratory Medicine, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea

Abstract

Background: Rapid antigen tests (RAT) of group A streptococci (GAS) are easy to perform and can save two days of bacterial culture time. Performance of SD Bioline Strep A was analyzed in comparison with throat culture.

Methods: Three consecutive throat swabs were taken from 308 healthy elementary schoolchildren. The first two swabs were tested for SD Bioline Strep A and Quidel Quick Vue Dipstick Strep A rapid antigen tests, and the third one was inoculated onto blood agar plate to grow GAS.

Results: Sensitivity, specificity, positive predictive value and negative predictive value of SD Bioline Strep A were 79.3%, 88.9%, 72.2%, and 92.2% respectively. Those of Quidel Quick Vue Strep A were 58.5%, 93.8%, 77.4%, and 86.2% respectively.

Conclusion: SD Bioline Strep A showed a significantly higher sensitivity and a slightly lower specificity compared to Quidel Quick Vue Strep A. SD Bioline Strep A RAT should be useful for the rapid diagnosis of bacterial pharyngitis and the optimum use of antibiotics. (Korean J Clin Microbiol 2007; 10:54-58)

Keywords

Streptococcus pyogenes, Group A streptococcus, Rapid antigen test, Throat culture, Pharyngitis