Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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pISSN 2288-0585 eISSN 2288-6850

Diagnostic Experience in the 3 Human Brucellosis Cases by the Microbiologic, Serologic and Gene Tests

Case report

Annals of Clinical Microbiology (Ann Clin Microbiol) 2007 October Volume 10, Issue 2, pages 154-159.


https://doi.org/10.5145/ACM.2007.10.2.154

Diagnostic Experience in the 3 Human Brucellosis Cases by the Microbiologic, Serologic and Gene Tests

Gyoung Yim Ha1, Young Sil Choi2, Moon Yeon Kim1, Young Hyun Lee3, Kyoung Seop Lee4, Kyu Jam Hwang2, Mi Yeon Pak2
Departments of 1Laboratory Medicine, 3Internal Medicine, and 4Urology, College of Medicine, Dongguk University, Gyeongju; 2Division of Zoonoses, Center for Immunology and Pathology, National Institute of Health, Seoul, Korea

Abstract

Brucellosis is a zoonosis caused by Brucella species. B. melitensis, B. suis, B. abortus and B. canis can infect humans. Recently, as the cases of bovine brucellosis have increased every year in Korea, the cases of human brucellosis have also increased among livestock workers and veterinarians in rural areas, since the first human case was reported in 2003. Because clinical manifestations of the disease are nonspecific and may be very atypical, clinicians and laboratory persons need to be active in using diagnostic tools including polymerase chain reaction in addition to the ordinary culture and serologic tests, and taking an appropriate measure to prevent intralaboratory infection. We report herein our experience in three human brucellosis cases diagnosed by cultures, serologic tests and gene detection. (Korean J Clin Microbiol 2007;10:154-159)

Keywords

 Human brucellosis, B. abortus, Diagnostic tools