Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

6

Weeks in Review

2

Weeks to Publication
Indexed in KCI, KoreaMed, Synapse, DOAJ
Open Access, Peer Reviewed
pISSN 2288-0585 eISSN 2288-6850

Characteristics of Microorganisms Isolated from Blood Cultures at a University Hospital Located in an Island Region During 2003∼2007

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2008 April Volume 11, Issue 1, pages 11-17.

https://doi.org/10.5145/ACM.2008.11.1.11

Characteristics of Microorganisms Isolated from Blood Cultures at a University Hospital Located in an Island Region During 2003∼2007

Sung Ha Kang, Young Ree Kim

Department of Laboratory Medicine, College of Medicine, Cheju National University, Jeju, Korea

Abstract

Background: The referral hospital is somewhat isolated from the mainland due to its island status; thus, microorganisms isolated from blood cultures might have a distinct pattern in their frequency and antibiogram. We attempted to uncover these characteristics.

Methods: The isolates from blood cultures at the Cheju University Hospital during 2003∼2007 were analysed. After inoculation in aerobic and anaerobic bottles, blood specimens were cultured using BacT/ Alert system, and the isolates were identifieded and antimicrobial susceptibilities were tested using Vitek II system.

Results: The overall positive rate of blood cultures was 9.6% and contamination rate was 3.6%. The most commonly isolated pathogens were Escherichia coli, Staphylococcus aureus, and Klebsiella pneumoniae. Gram positive rod, gram negative cocci, and anaerobes were not isolated, but fungi were isolated in 0.6% of blood cultures. The prevalence of methicillin-resistant S. aureus (MRSA) was 68.0% in 2003, 41.4% in 2004, 48.1% in 2005, 54.5% in 2006, and 65.2% in 2007. The prevalence of vancomycin-resistant enterococcus (VRE) was 0% in 2003 and 2004, 16.7% in 2005, 10.0% in 2006, and 9.5% in 2007.

Conclusion: The most commonly isolated pathogens were similar to those from other hospitals, but the isolation rates of MRSA and VRE by year showed different patterns. Also, gram positive rods, gram negative cocci and anaerobes were not isolated. To help the choice of empirical antibiotic treatments, we need complementary measures to upgrade microorganism isolation systems and further studies including the monitoring of antibiotic use. (Korean J Clin Microbiol 2008;11:11-17)

Keywords

Blood culture, Positive rate, Contamination, Antimicrobial susceptibility