Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Microbiological Characteristics of Methicillin-resistant Staphylococcus aureus

Review article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2010 March, Volume 13, Issue 1, pages 1-6.

https://doi.org/10.5145/ACM.2010.13.1.1

Microbiological Characteristics of Methicillin-resistant Staphylococcus aureus

Jongyoun Yi1,*, Eui-Chong Kim1,2
1Department of Laboratory Medicine, Seoul National University Hospital, 2Department of Laboratory Medicine, Seoul National University College of Medicine, Seoul, Korea

Abstract

Methicillin-resistant Staphylococcus aureus (MRSA) is a typical pathogen of nosocomial infection, and has recently emerged as an important community-acquired pathogen. MRSA is notorious as a multidrug- resistant organism. Its resistance to all β-lactams is mediated by PBP2a which is encoded by mecA, and it is also resistant to many antimicrobials of other classes due to frequently co-carrying resistance genes, which accounts for becoming a clinical and laboratory issue. This article reviews the microbiological characteristics, surveillance methods, and molecular epidemiology of MRSA. (Korean J Clin Microbiol 2010;13:1-6)

Keywords

Methicillin-resistant Staphylococcus aureus, mecA, Carrier state, Molecular epidemiology