Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology


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pISSN 2288-0585 eISSN 2288-6850

Clostridium symbiosum Isolated from Blood

Case report

Annals of Clinical Microbiology (Ann Clin Microbiol) 2010 June, Volume 13, Issue 2, pages 90-92.

Clostridium symbiosum Isolated from Blood

Hee Jae Huh, Seung Tae Lee, Jang Ho Lee, Chang Seok Ki, Nam Yong Lee

Department of Laboratory Medicine and Genetics, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea


Clostridium symbiosum was isolated from the blood of a 61-year-old immunocompromised woman who had diagnosed ovarian cancer with multiple metastases and who had developed persistent tachycardia. A blood culture was drawn from the peripherally inserted central catheter, and non-spore-forming gram-negative rods were detected in an anaerobic vial. The organism showed tiny and pinpoint colonies and was unidentified by Vitek II (bioMerieux, France). The 16S rRNA gene sequence showed a 99.4% identity with C. symbiosum. To our knowledge, this represents the first report of C. symbiosum isolation in Korea. (Korean J Clin Microbiol 2010;13: 90-92)


Clostridium symbiosum, Immunocompromised patient, Gram’s stain, 16S rRNA sequencing