Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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pISSN 2288-0585 eISSN 2288-6850

Comparison of Antibiotic Resistance Rate of Medically Important Microorganisms between Japan and Korea

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2015 December, Volume 18, Issue 4, pages 111-118.

https://doi.org/10.5145/ACM.2015.18.4.111

Comparison of Antibiotic Resistance Rate of Medically Important Microorganisms between Japan and Korea

Keigo Shibayama1*, Hyukmin Lee2*, Sunjoo Kim3
1Department of Bacteriology II, National Institute of Infectious Diseases, Tokyo, Japan, 2Department of Laboratory Medicine, Catholic Kwangdong University, Incheon, 3Department of Laboratory Medicine, Gyeongsang National University School of Medicine, Gyeongsang Health Science Institute, Jinju, Korea

Abstract

Background: A surveillance system for antibiotic resistance is well organized in both Japan and Korea; however, a comparative analysis by microorganism has not previously been conducted.

Methods: We compared the latest antibiotic resistance rates of medically important pathogens, such as Staphylococcus aureus, enterococci, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Acinetobacter baumannii, between Japan and Korea. Data were collected by JANIS (Japan Nosocomial Infections Surveillance) and KARMS (Korean Antimicrobial Resistance Monitoring System) from 2007-2012.

Results: In 2012, the proportions of oxacillin-resistant S. aureus, vancomycin-resistant Enterococcus faecium (VRE), cefotaxime-resistant E. coli, ceftazidime-resistant K. pneumoniae, imipenem-resistant P. aeruginosa, and imipenem-resistant A. baumannii were 53%, 0.4%, 16.6%, 2.9%, 18.5%, and 2% in Japan and 67%, 32%, 29%, 40%, 28%, and 70% in Korea, respectively.

Conclusion: There were large differences in the frequencies of VRE, ceftazidime-resistant K. pneumoniae, and imipenem-resistant A. baumannii between Japan and Korea. A collaborative study to probe the differences in the antibiotic resistance rates between the two countries should be performed. (Ann Clin Microbiol 2015;18:111-118)

Keywords

Acinetobacter baumannii, Carbapenem, Resistance, Methicillin-resistant Staphylococcus aureus, Vancomycin-resistant enterococci