Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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pISSN 2288-0585 eISSN 2288-6850

Two Cases of Medical Device-Related Corynebacterium striatum Infection: A Meningitis and A Sepsis

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2016 March, Volume 19, Issue 1, pages 28-31.

https://doi.org/10.5145/ACM.2016.19.1.28

Two Cases of Medical Device-Related Corynebacterium striatum Infection: A Meningitis and A Sepsis

Sholhui Park1, Hae-Sun Chung1, Eui Kyo Seo2, Yeung Chu Mun3, Miae Lee1
Departments of lLaboratory Medicine, 2Neurosurgery, 3Internal Medicine, Ewha Womans University School of Medicine, Seoul, Korea

Abstract

Corynebacterium striatum is a commonly isolated contaminant in the clinical microbiology. However, it can be an opportunistic pathogen in immunocompromised and even immunocompetent hosts. The increasing prevalence of C. striatum infection has been associated with immunosuppression and prosthetic devices. We report a case of meningitis with cerebrospinal fluid drainage and a case of catheter-related bloodstream infection caused by C. striatum. The isolates were identified as nondiphtherial Corynebacterium species by VITEK 2 (bioMérieux, France) anaerobe and Corynebacterium card. The final identification by 16S rRNA gene sequencing analysis was C. striatum with 99.7% identity and 99.6% identity with C. striatum ATCC 6940, respectively. Both strains were sensitive to vancomycin and gentamicin, but multidrug-resistant to ciprofloxacin, penicillin, erythromycin and imipenem. (Ann Clin Microbiol 2016;19:28-31)

Keywords

Bloodstream infection, Corynebacterium striatum, Meningitis, 16S rRNA gene sequencing