Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology


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pISSN 2288-0585 eISSN 2288-6850

First Case of Psychrobacter sanguinis Bacteremia in a Korean Patient

Case report

Annals of Clinical Microbiology (Ann Clin Microbiol) 2017 September, Volume 20, Issue 3, pages 74-79.

First Case of Psychrobacter sanguinis Bacteremia in a Korean Patient

Sangeun Lim1, Hui-Jin Yu1, Seungjun Lee1, Eun-Jeong Joo2, Joon-Sup Yeom2, Hee-Yeon Woo1, Hyosoon Park1, Min-Jung Kwon1
1Department of Laboratory Medicine and 2Division of Infectious Diseases, Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea


Psychrobacter sanguinis has been described as a Gram-negative, aerobic coccobacilli originally isolated from environments and seaweed samples. To date, 6 cases of P. sanguinis infection have been reported. A 53-year-old male was admitted with a generalized tonic seizure lasting for 1 minute with loss of consciousness and a mild fever of 37.8oC. A Gram stain revealed Gram-negative, small, and coccobacilli- shaped bacteria on blood culture. Automated microbiology analyzer identification using the BD BACTEC FX (BD Diagnostics, Germany) and VITEK2 (bioMérieux, France) systems indicated the presence of Methylobacterium spp., Aeromonas salmonicida, and the Moraxella group with low discrimination. The GenBank Basic Local Alignment Search Tool and an Ez-Taxon database search revealed that the 16SrRNA gene sequence of the isolate showed 99.30% and 99.88% homology to 859 base-pairs of the corresponding sequences of P. sanguinis, respectively (GenBank accession numbers JX501674.1 and HM212667.1). To the best of our knowledge, this is the first human case of P. sanguinis bacteremia in Korea. It is notable that we identified a case based on blood specimens that previously had been misidentified by a commercially automated identification analyzer. We utilized 16S rRNA gene sequencing as a secondary method for correctly identifying this microorganism. (Ann Clin Microbiol 2017;20:74-79)


Bacteremia, Psychrobacter sanguinis, 16S ribosomal RNA