Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology
Case report

Nocardia abscessus Cutaneous Abscess: A Case Report and Review of the Literature

Hee Sue Park1, Bo Ra Son2, Min Suk Song3, Kyeong Seob Shin2

1Department of Laboratory Medicine, Chungbuk National University Hospital, Departments of 2Laboratory Medicine and 3Microbiology, Chungbuk National University College of Medicine, Cheongju, Korea

Corresponding to Kyeong Seob Shin, E-mail: ksshin@chungbuk.ac.kr

Ann Clin Microbiol 2018;21(3):64-67. https://doi.org/10.5145/ACM.2018.21.3.64
Copyright © Korean Society of Clinical Microbiology.

Abstract

We describe a cutaneous abscess caused by Nocardia abscessus in a previously healthy woman. A 74- year-old woman presented with recurrent bullae on her left forearm that developed 1 week prior and was initially suspected to be a cutaneous infection with Mycobacteria or Tinea corporis. Histopathologically, the skin lesion formed an abscess. A smear revealed a few branched Gram-positive filamentous microorganisms that formed a creamy white colony on a blood agar plate after incubation for 3 days. The colony tested negative on acid-fast bacilli (AFB) staining, but was positive on modified AFB staining. The isolate was confirmed to be N. abscessus by 16S rRNA sequencing analysis. The isolate was susceptible to trimethoprim-sulfamethoxazole, amikacin, cefotaxime and erythromycin but resistant to penicillin. The patient was treated with clarithromycin but subsequently lost to follow-up. To the best of our knowledge, this is the first report of a human cutaneous infection with N. abscessus in Korea. (Ann Clin Microbiol 2018;21:64-67)

Keywords

Cutaneous abscess, Nocardia abscessus, 16S rRNA sequence