Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Indexed in KCI, KoreaMed, Synapse, DOAJ
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pISSN 2288-0585 eISSN 2288-6850

A Case Report of Saccharomyces cerevisiae Fungemia in a Premature Infant Following Probiotic Treatment

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2020 September, Volume 23, Issue 3, pages 215-218.

https://doi.org/10.5145/ACM.2020.23.3.5

A Case Report of Saccharomyces cerevisiae Fungemia in a Premature Infant Following Probiotic Treatment

Jaewoong Lee1, Hyunjung Kim1, Hae Kyung Lee1, Yeon-Joon Park2
Department of Laboratory Medicine, 1Uijeongbu St. Mary’s Hospital, Uijeongbu, 2Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea

Abstract

Probiotics are used to restore and maintain the healthy intestinal microflora. Although Saccharomyces cerevisiae (SC) is considered as a non-pathogenic yeast, administration of SC as a probiotic is associated with a rare cause of fungemia in immunocompromised patients with central venous catheter insertion. We encountered a case of SC fungemia in a premature infant who presented with respiratory distress syndrome and had undergone central venous catheterization.

Keywords

Central venous catheter, Fungemia, Premature birth , Probiotics, Saccharomyces cerevisiae