Table 1. Distribution of molecular types of Cryptococcus neoformans and Cryptococcus gattii isolates from Korea, Japan, and China by multilocus sequence typing
Ann Clin Microbiol 2024;27(4):257-265. Current epidemiology and implication for microbiological diagnosis of cryptococcal infections in Korea Download table Country Source Molecular type Reference VNI VNII VNIV VGI VGII VGIII ST4 ST5 ST31 ST32 ST38 ST53 ST63 ST191 ST359 ST360 ST43 ST127 ST57 ST159 ST7 ST21 ST44 ST126 ST173 ST113 Korea Clinical 32 4 […]
Table 3. Characteristics of several molecular diagnostics for candidemia approved by Conformité Européenne/ In Vitro Diagnostic or Food and Drug Administration
Ann Clin Microbiol 2024;27(4):245-255. Current nonculture-based diagnosis of candidemia Download table Commercial kit Manufacturer Detectable Candida species Needs of nucleic acid extraction Principle Available specimen Assay time Reference eplex® BCID FP Panela) GenMark Dx C. albicans, C. dubliniensis, C. famata, C. glabrata, C. guilliermondii, C. kefyr, P. kudriavzevii, C. lusitaniae, C. parapsilosis, C. tropicalis, C. […]
Table 2. Characteristics of several immunological diagnostics for candidemia
Ann Clin Microbiol 2024;27(4):245-255. Current nonculture-based diagnosis of candidemia Download table General target Function Available commercial kit Overall sensitivity (95% CI) Overall specificity (95% CI) Reference Candida (1,3)-β-D-glucan Candida Cell wall component Fungitell; Wako; Fungitec-G; Dynamiker Fungus 0.81 (0.75-0.86) 0.64 (0.55-0.71) [11] Candida mannan Candida Cell wall component Platelia Candida Ag-Plus and Ab-Plus; Serion Mannan […]
Table 1. Characteristics of nonculture-based diagnostics for candidemia
Ann Clin Microbiol 2024;27(4):245-255. Current nonculture-based diagnosis of candidemia Download table Method Target or principle of assay Advantage Shortcoming Antigen detection-based immunological assay Candida (1,3)-β-D-glucan Rapid, high sensitivity, high negative predictive value Low specificity, high false-positive Candida mannan Rapid, earlier diagnosis of candidemia Low sensitivity Antibody-based immunological assay Anti-mannan Ab; C. albicans germ tube antibody […]
Table 2. Summary of the microbiological studies of the clinical isolates of Candida auris in Korea
Ann Clin Microbiol 2024;27(4):231-244. Candida and candidemia in Korea Download table Year of publication No. of patient (No. of isolate) Specimen (No. of isolate) Molecular epidemiologic test (No. of isolate)a Resistance rate of antifungal agent (%)b Possible genetic marker of FLU resistant isolate Reference FLU AMB CSF MCF ANF 2009 15 (15) Ear (15) NT […]
Table 1. Studies describing the azole antifungal resistance mechanisms in the Candida isolates collected from Korean multicenter studies.
Ann Clin Microbiol 2024;27(4):231-244. Candida and candidemia in Korea Download table Candida species C. albicans C. tropicalis C. parapsilosis C. glabrata C. auris Collection period of isolates 2006–2021 2003–2013 2005–2016 2008–2018 1996–2022 Number of hospitals 10 8 8 19 13 Number of isolates 26 BSI (14 FNS and 12 FS) isolates 9 FNS, 12 FS […]
Fig. 2. Antifungal resistance of the Candida bloodstream infection isolates from Korean hospitals using new clinical breakpoints (CLSI M60-ED2:2020) [36].
Ann Clin Microbiol 2024;27(4):231-244. Candida and candidemia in Korea Download image
Fig. 1. Species distribution of the Candida bloodstream infection isolates from Korean hospitals.
Ann Clin Microbiol 2024;27(4):231-244. Candida and candidemia in Korea Download image
Table 1. Key approaches in the polyphasic fungal identification
Ann Clin Microbiol 2024;27(4):221-230. Fungal identification based on the polyphasic approach: a clinical practice guideline Download table Categories Contents Phenotypic-based approach Morphological characteristics – Sporulation organ structures (e.g., conidia, macroconidia).– Colony traits: growth rate, aerial mycelium, odor.– Cultivation conditions (e.g., medium composition, temperature).– Microscopy: with/without staining, DIC microscopy. Biochemical and physiological characteristics […]
Fungal infections: rising threats, diagnostic challenges, and the path forward for clinical microbiology laboratories
Editorial Jayoung Kim Department of Laboratory Medicine, International St. Mary’s Hospital, College of Medicine, Catholic Kwandong University, Incheon, Korea Corresponding to Jayoung Kim, E-mail: lmkjy7@gmail.com Ann Clin Microbiol 2024;27(4):217-219. https://doi.org/10.5145/ACM.2024.27.4.1Received on 17 December 2024, Revised on 19 December 2024, Accepted on 19 December 2024, Published on 20 December 2024.Copyright © Korean Society of Clinical Microbiology.This […]