Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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Pulmonary Fungal Ball of Pseudallescheria boydii Identified by LSU rDNA D2 Region Sequencing

Case report

Annals of Clinical Microbiology (Ann Clin Microbiol) 2009 June, Volume 12, Issue 2, pages 87-91.

https://doi.org/10.5145/ACM.2009.12.2.87

Pulmonary Fungal Ball of Pseudallescheria boydii Identified by LSU rDNA D2 Region Sequencing

Miyoung Kim, Mi-Hee Ahn, Ji Sang Kang, Hyun Lee, Sei-Ick Joo, Sung Sup Park, Eui-Chong Kim

Department of Laboratory Medicine, Seoul National University Hospital, Seoul, Korea

Abstract

We report a case of pulmonary fungal ball of Pseudallescheria boydii (Scedosporium apiospermum, the anamorph) and the result of LSU rDNA D2 region sequencing of the clinical isolate. An immunocompetent 58-year-old female suffered 2-year history of hemoptysis. Her symptom persisted despite the administration of oral itraconazole, even though the clinical, radiological, and histological findings suggested Aspergilloma. In the fungal culture, the typical morphology of S. apiospermum was observed. Even though the sequencing using LSU rDNA D2 region identified the organism as Pseudallescheria ellipsoidea, one of the P. boydii complex, the further investigation of ours suggested that the species in P. boydii complex could not be differentiated from each other by the sequencing of LSU rDNA D2 region. (Korean J Clin Microbiol 2009;12:87-91)

Keywords

Scedosporium apiospermum, Pseudallescheria boydii, Pseudallescheria ellipsoidea