Annals of Clinical Microbiology, The official Journal of the Korean Society of Clinical Microbiology

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A Case of Prosthetic Valve Endocarditis with Cerebral Hemorrhage Caused by Rothia mucilaginosa

Original article

Annals of Clinical Microbiology (Ann Clin Microbiol) 2020 December, Volume 23, Issue 4, pages 271-276.

https://doi.org/10.5145/ACM.2020.23.4.6

A Case of Prosthetic Valve Endocarditis with Cerebral Hemorrhage Caused by Rothia mucilaginosa

Yeo-Jin Song1*, Bongyoung Kim1*, Young-eun Kim2, Yangsoon Lee2, Hyunjoo Pai1
1Department of Internal Medicine, 2Department of Laboratory Medicine, Hanyang University College of Medicine, Seoul, Korea

Abstract

Rothia spp. are aerobic, gram-positive cocci belonging to the family Micrococcaceae, and are a part of the normal microbial flora of the human oropharynx and upper respiratory tract. We present the first case of the prosthetic valve endocarditis with cerebral hemorrhage caused by Rothia mucilaginosa in South Korea. A 65-year-old man with a prosthetic aortic valve visited the outpatient clinic with a complaint of fever. R. mucilaginosa was identified in one among four sets of blood culture bottles obtained on the on day 30 of fever onset. Brain magnetic resonance imaging (MRI) showed multiple micro-hemorrhages suggesting septic emboli in both the hemispheres, corticomedullary junctions, and cerebellum. Rothia spp. should be considered as a possible pathogen in the cases of infective endocarditis with intracranial hemorrhage.

Keywords

Cerebral hemorrhage, Infective endocarditis, Prosthetic valve, Rothia mucilaginosa