Principles and clinical applications of interferon-gamma release assays in latent tuberculosis diagnosis
Review article Ha-eun Cho1, Young Jin Kim2 1Department of Laboratory Medicine, Kyung Hee University Hospital, Seoul, Korea2Department of Laboratory Medicine, Kyung Hee University College of Medicine, Kyung Hee University Hospital, Seoul, Korea Correspondence to Young Jin Kim, E-mail: khmclab@gmail.com Ann Clin Microbiol 2025;28(3):17. https://doi.org/10.5145/ACM.2025.28.3.6Received on 7 July 2025, Revised on 4 September 2025, Accepted on […]
Challenges and advances in mycobacterial molecular typing
Review article Minh Phuong Trinh, Min-Kyoung Shin Department of Microbiology and Convergence Medical Science, College of Medicine, Gyeongsang National University, Jinju, Korea Correspondence to Min-Kyoung Shin, E-mail: mkshin@gnu.ac.kr Ann Clin Microbiol 2025;28(3):18. https://doi.org/10.5145/ACM.2025.28.3.7Received on 22 July 2025, Revised on 22 August 2025, Accepted on 28 August 2025, Published on 20 September 2025.Copyright © Korean Society […]
Introduction to the special issue on current trends in laboratory diagnosis and public health of mycobacterial diseases in Korea and highlights in this issue
Editorial Hae-Sun Chung Department of Laboratory Medicine, Ewha Womans University College of Medicine, Seoul, Korea Correspondence to Hae-Sun Chung, E-mail: sunny0521.chung@ewha.ac.kr Ann Clin Microbiol 2025;28(3):19. https://doi.org/10.5145/ACM.2025.28.3.8Received on 12 September 2025, Revised on 15 September 2025, Accepted on 16 September 2025, Published on 20 September 2025.Copyright © Korean Society of Clinical Microbiology.This is an Open Access […]
Table 6. Characteristic of line probe assays for the identification of nontuberculous mycobacteria
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Assay Manufacturer Target Intended use Species GenoType Mycobacterium CM/AS Bruker 23 rRNA gene Culture only CM Ver 2.0MTBC, M. avium, M. intracellulare, M. chelonae, M. abscessus complex, M. fortuitum group,M. gordonae, M. scrofulaceum, M. szulgai, M. interjectum, M. kansasii, […]
Table 5. Commercial molecular assays assays for M. tuberculosis complex
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Assay Type Gene Target Manufacturer, headquarters Amplified Mycobacterium Tuberculosis Direct (AMTD) test isothermal transcriptase-mediated amplification assay 16S rRNA gene Detection of MTBC Hologic, Canada AdvanSure TB/NTM real-time PCR kit Real-time PCR IS6110 insertion sequence for MTBCITS regions for NTM […]
Table 4. Characteristics of three MALDI-TOF MS systems for mycobacteria
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Company Vitek MS PRIME MALDI Biotyper Sirius IDSys LT® bioMérieux Bruker Daltonics ASTA Panel Disposable slide with 48 positions 192 isolates can be tested per run Reuseable slide with 96 well Disposable or reuseable 6 × 16 μFocus Plate […]
Table 3. Characteristics of immunochromatography assays for M. tuberculosis complex
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Assay Type Target Time to result Media Performance Manufacturer, headquarters SD BiolineTM TB Ag MPT64 Device MPT64 Ag 15 min Solid cultureLiquid culture Sensitivity: 98.6%Specificity: 100% Abbott, Korea STANDARD Q TB MPT64 Ag Device MPT64 Ag 10 min Solid […]
Table 2. Current status of mycobacterial testing in clinical laboratories in South Korea
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Methods No. % AFB smear (n = 238) Ziehl–Neelsen 127 53.4 Fluorochrome 110 46.2 Kinyoun 1 0.4 Culture – solid media (n = 123) Ogawa 115 93.5 Lowenstein-Jensen 8 6.5 Culture – liquid media (n […]
Table 1. Classification of mycobacteria proposed by Gupta et al. [10] in 2018
Ann Clin Microbiol 2025;28(3):16. Current status of mycobacterial identification in clinical laboratories in Korea Download table Group Genus Clade Species Slow-growing Mycobacterium “Tuberculosis-Simiae” clade M. tuberculosis complex, M. avium complex,M. intracellulare, M. gordonae clade,M. kansasii clade, M. arupense,M. lentiflavum, M. simiae clade,M. scrofulaceum, M. parascrofulaceum,M. gastri, M. interjectum,as well as several other slow-growing species Mycolicibacter […]
Complete genome analysis of representative methicillin-resistant Staphylococcus aureus clinical strains prevalent in Korea during 2014-2017
Original article Harshad Lade1*, Tae-Im Kim1*, Jung-Min Kim1, Yong-Kyun Kim2, Kibum Jeon3, Hyun Soo Kim4, Han-Sung Kim5, Wonkeun Song6, Jae-Seok Kim1 1Department of Laboratory Medicine, Hallym University College of Medicine, Kangdong Sacred Heart Hospital, Seoul, Korea2Department of Laboratory Medicine, Sahmyook Medical Center, Seoul, Korea3Department of Laboratory Medicine, Hallym University College of Medicine, Hangang Sacred Heart […]