Fig. 3. Correlation of toxin B gene cycle threshold values from Allplex GI-Bacteria(I) and Xpert C. difficile assays. PCR, polymerase chain reaction.
Ann Clin Microbiol 2026;29(1):1. Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study Download image
Fig. 2. Area under curve (AUC) of C. Diff Quik Chek Complete and RIDASCREEN C. difficile GDH and toxin A/B. (A) AUC of GDH; (B) AUC of toxin A/B. QCC, C. Diff Quik Chek Complete; RIDA, RIDASCREEN C. difficile assay; GDH, glutamate dehydrogenase.
Ann Clin Microbiol 2026;29(1):1. Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study Download image
Fig. 1. Sensitivity and specificity of C. Diff Quik Chek Complete and RIDASCREEN C. difficile GDH and toxin A/B. QCC, C. Diff Quik Chek Complete; RIDA, RIDASCREEN C. difficile assay; X-axis, percentages.
Ann Clin Microbiol 2026;29(1):1. Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study Download image
Table 2. Results of Allplex GI-Bacteria(I) and Xpert C. difficile assays in 26 EIA-discordant samples
Ann Clin Microbiol 2025;29(1):1. Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study Download table QCC RIDA Allplex GI-Bacteria(I) assay (Toxin B) Xpert C. difficile assay (Toxin B) No. of specimens GDH Toxin A/B GDH Toxin A/B […]
Table 1. The performance of C. Diff Quik Chek Complete and RIDASCREEN C. difficile GDH and toxin A/B
Ann Clin Microbiol 2025;29(1):1. Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study Download table Sensitivity(95% CI) Specificity(95% CI) Positive likelihood ratio(95% CI) Negative likelihood ratio(95% CI) AUC(95% CI, P) PPV(95% CI) NPV(95% CI) Accuracy(95% CI) […]
Performance of C. Diff Quik Chek Complete and RIDASCREEN immunoassays and lack of Ct value concordance between Allplex GI-Bacteria(I) and Xpert Clostridioides difficile assays: a diagnostic accuracy study
Original article Kibum Jeon1, Nuri Lee2, Hyun Soo Kim3, Han-Sung Kim4, Wonkeun Song2, Jae-Seok Kim5 1Department of Laboratory Medicine, Hallym University College of Medicine, Hallym University Hangang Sacred Heart Hospital, Seoul, Korea2Department of Laboratory Medicine, Hallym University College of Medicine, Hallym University Kangnam Sacred Heart Hospital, Seoul, Korea3Department of Laboratory Medicine, Hallym University College of […]
Table 2. Human infections due to Segniliparus spp., including the present case, with identification method, risk factors, DST, and outcomes
Ann Clin Microbiol 2025;29(1):2. Pulmonary infection caused by Segniliparus rugosus in a patient without systemic immunodeficiency but with bronchiectasis: first identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with whole-genome confirmation Download table Author (year) Species Identification method Risk factor DST Outcome Butler et al. (2007) [2] S. rugosus (3 cases) 16S rRNA sequencing CF BMD in Middlebrook […]
Table 1. Antimicrobial susceptibility of the S. rugosus clinical isolate
Ann Clin Microbiol 2025;29(1):2. Pulmonary infection caused by Segniliparus rugosus in a patient without systemic immunodeficiency but with bronchiectasis: first identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with whole-genome confirmation Download table Antimicrobial agent MIC (μg/mL) Interpretation a) Clarithromycin > 32 R Amikacin > 128 R Moxifloxacin 2 I Linezolid 16 I Streptomycin 64 N/A Ciprofloxacin ≤ […]
Fig. 2. Phylogenomic placement of the clinical Segniliparus rugosus isolate by Type Strain Genome Server (TYGS). A genome-based tree was generated with the TYGS (accessed September 5, 2025) using Genome BLAST Distance Phylogeny (GBDP) distances and FastME. The isolate clustered within the S. rugosus clade together with the type strain, supporting the species assignment. The tree was visualized using iTOL v7. Node labels indicate GBDP pseudo-bootstrap support values (only ≥ 50% are shown), and the scale bar indicates GBDP distance.
Ann Clin Microbiol 2025;29(1):2. Pulmonary infection caused by Segniliparus rugosus in a patient without systemic immunodeficiency but with bronchiectasis: first identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with whole-genome confirmation Download image
Fig. 1. Colony morphology and acid-fast staining of Segniliparus rugosus. (A) Colonies on Ogawa medium. Rough, dry, buff-to-orange colonies. (B) Acid-fast bacillus stain (colony smear). Strongly acid-fast short rods were observed, unlike Nocardia spp., which are typically weakly/ partially acid-fast and show branching filaments.
Ann Clin Microbiol 2025;29(1):2. Pulmonary infection caused by Segniliparus rugosus in a patient without systemic immunodeficiency but with bronchiectasis: first identification by matrix-assisted laser desorption ionization time-of-flight mass spectrometry with whole-genome confirmation Download image